Results 71 to 80 of about 343,485 (300)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Boundary-mode operation of the boost converter for thermoelectric generator maximum power tracking [PDF]

, 2014
This article has been made available through the Brunel Open Access Publishing Fund.Performance-favourable and noteworthy characteristics of the Boost converter are reported, when the latter operates in Maximum Power Tracking (MPT) mode, while fed from a
Theodoridis, M
core  

Operation and control of a current source converter series tapping of an LCC-HVDC link for integration of offshore wind power plants [PDF]

, 2016
This work presents a series tapping station for integrating Offshore Wind Power Plants (OWPP) into a (Line Commutated Converter High Voltage Direct Current) LCC-HVDC transmission system.
Galceran Arellano, Samuel, Gomis Bellmunt, Oriol, Prieto Araujo, Eduardo, Sau Bassols, Joan   +3 more
core   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Generalized Parametric Design of an Integrated Electric Vehicle Drive System for Wide-Speed-Range Operation: Experimental Validation, Torque Control, and Performance Assessment

IEEE Access
Existing research on electric vehicles (EVs) predominantly addresses component sizing for the electric vehicle drivetrain system (EVDS) without adequate validation of dynamic performance under integrated traction motor (TM) control.
Mahmoud M. Akl, Jose Rodriguez, Mohamed Abdelrahem, Abdelsalam A. Ahmed   +3 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Power quality issues of 3MW direct-driven PMSG wind turbine [PDF]

, 2015
This paper presents power quality issues of a grid connected wind generation system with a MW-class direct-driven permanent magnet synchronous generator (PMSG).
Ahmed, IA, Taylor, GA, Zobaa, AF
core   +1 more source

Enhanced Modulated Model Predictive Control for Matrix Converters in Overmodulation Zones

IEEE Open Journal of Power Electronics
Modulated Model Predictive Control (MMPC) techniques can be applied to enhance matrix converter (MC) performance in the linear modulation zone (LMZ). However, extending the converter operation in the overmodulation zone (OMZ) remains a problem.
Ali Sarajian, Quanxue Guan, Ibrahim Harbi, Davood Arab Khaburi, Ralph Kennel, Cristian Garcia, Patrick Wheeler, Jose Rodriguez   +7 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source