Results 81 to 90 of about 957,228 (296)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A low-cost parallel computing platform for power engineering applications [PDF]
APSCOM 2000 - 5th International Conference on Advances in Power System Control, Operation and Management, 2000 This paper develops and evaluates a low-cost parallel computing platform for the implementation of parallel algorithms in Power Engineering applications. The proposed approach utilises an existing local area network without incurring any additional hardware costs.
openaire +1 more source
Deriving stencil hardware accelerators from a single higher-order function [PDF]
, 2014 Stencil computations are array based algorithms that apply a computation to all array elements in a fixed regular pattern and can be found in many scientific and engineering applications.
Kuper, Jan, Wester, Rinse
core +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Energy aware execution environments and algorithms on low power multi-core architectures [PDF]
, 2016 Proceedings of the First PhD Symposium on Sustainable Ultrascale Computing Systems (NESUS PhD 2016) Timisoara, Romania. February 8-11, 2016.Energy consumption is a key aspect that conditions the proper functioning of nowadays data centers and high ...
Catalán, Sandra +2 more
core +2 more sources
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Numerical propulsion system simulation: An interdisciplinary approach [PDF]
The tremendous progress being made in computational engineering and the rapid growth in computing power that is resulting from parallel processing now make it feasible to consider the use of computer simulations to gain insights into the complex ...
Chamis, Christos C., Nichols, Lester D.
core +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
When Mobile Blockchain Meets Edge Computing
, 2018 Blockchain, as the backbone technology of the current popular Bitcoin digital currency, has become a promising decentralized data management framework.
Han, Zhu +4 more
core +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source