Results 31 to 40 of about 5,016,217 (299)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

A Power Transistor Active Gate Driver With Two-Level Miller Plateau Detection and Driving Device Equalization Using 180-nm HV BCD Process

IEEE Open Journal of Circuits and Systems
The configuration of the active gate driver (AGD) significantly impacts how well power semiconductor devices work and how efficient they are. This research presents a new AGD single chip design that identifies the Miller plateau when the signal is ...
Chua-Chin Wang, Pradyumna Vellanki, Venkata Naveen Kolakaluri, L S S Pavan Kumar Chodisetti, Lean Karlo Santos Tolentino, Mitch Ming-Chi Chou, Oliver Lexter July Alvarez Jose   +6 more
doaj   +1 more source

Power Gating Technique for Power Reduction and Data Retention in CMOS Circuits [PDF]

Journal of Electrical and Electronics Engineering, 2016
Usage of battery powered hand held devices has been increasing in this modern era. To extend the battery life of these devices, more aggressive power reduction techniques are necessary.
MANICKAM Kavitha, THANGAVEL Govindaraj
doaj  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Low-Power AES Data Encryption Architecture for a LoRaWAN

IEEE Access, 2019
In recent years, the Internet of Things (IoT) has significantly increased the number of Internet connections to a large number of objects in different domains, including industry, homes and transportation.
Kun-Lin Tsai, Fang-Yie Leu, Ilsun You, Shuo-Wen Chang, Shiung-Jie Hu, Hoonyong Park   +5 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Characterization of nonlinear switching in a figure-of-eight fiber laser using frequency-resolved optical gating [PDF]

, 1998
The measurement technique of frequency-resolved optical gating is applied to determine the nonlinear switching characteristics of a passively modelocked figure-of-eight erbium-doped fiber laser. By completely characterizing the intensity and phase of the
Barry, Liam P., Bollond, Paul G., Dudley, John M., Leonhardt, Rainer, Harvey, John D.   +4 more
core   +2 more sources