Results 71 to 80 of about 1,709,190 (338)

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

On the definition of cyber-physical resilience in power systems [PDF]

Renewable and Sustainable Energy Reviews, 2016
20 pages.
Reza Arghandeh, Alexandra von Meier, Laura Mehrmanesh, Lamine Mili   +3 more
openaire   +4 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Diverging nonlocal fields: Operationalizing critical disability physics identity with neurodivergent physicists outside academia

Physical Review Physics Education Research
Science, technology, engineering, and mathematics (STEM) education research and physics education research, in particular, are currently struggling with a dearth of research into understanding the experiences and identity development of neurodivergent ...
Liam G. McDermott, Nazeer A. Mosley, Geraldine L. Cochran   +2 more
doaj   +1 more source

Virtual‐physical power flow method for cyber‐physical power system contingency and vulnerability assessment

IET Smart Grid, 2023
AbstractTraditional power systems have evolved into cyber‐physical power systems (CPPS) with the integration of information and communication technologies. CPPS can be considered as a typical hierarchical control system that can be divided into two parts: the power grid and the communication network.
Dongmeng Qiu, Rui Zhang, Zhuoran Zhou, Jinning Zhang, Xin Zhang   +4 more
openaire   +2 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Suppression of absence seizures by using different stimulations in a reduced corticothalamic-basal ganglion-pedunculopontine nucleus model

Mathematical Biosciences and Engineering, 2023
Coupled neural network models are playing an increasingly important part in the modulation of absence seizures today. However, it is currently unclear how basal ganglia, corticothalamic network and pedunculopontine nucleus can coordinate with each other ...
Xiaolong Tan, Rui Zhu, Yan Xie, Yuan Chai   +3 more
doaj   +1 more source

Imprints of Short Distance Physics On Inflationary Cosmology [PDF]

, 2001
We analyze the impact of certain modifications to short distance physics on the inflationary perturbation spectrum. For the specific case of power-law inflation, we find distinctive -- and possibly observable -- effects on the spectrum of density ...
A. Kempf, A. Kempf, A.A. Starobinsky, A.G. Cohen, A.H. Guth, Brian R. Greene, D. Amati, D. Gross, G. Shiu, G. Shiu, G. Veneziano, Gary Shiu, I. Antoniadis, J. Adams, J. Bardeen, J. Martin, J.C. Niemeyer, J.C. Niemeyer, L. Hui, M.S. Turner, N. Arkani-Hamed, R. Corless, R. Easther, R. Guida, R.H. Brandenberger, Richard Easther, S.W. Hawking, V.F. Mukhanov, V.F. Mukhanov, V.F. Mukhanov, V.F. Mukhanov, V.S. Kaplunovsky, V.S. Kaplunovsky, William H. Kinney   +33 more
core   +2 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Inhibition of absence seizures in a reduced corticothalamic circuit via closed-loop control

Electronic Research Archive, 2023
Inhibition of spike-wave discharges (SWD) was thought to be associated with remission of seizure symptoms in absence epilepsy. In the previous studies, pulse stimulation was applied directly to the brain as an effective means to inhibit SWD.
Yan Xie , Rui Zhu, Xiaolong Tan , Yuan Chai   +3 more
doaj   +1 more source