Results 91 to 100 of about 18,501,661 (355)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Sparse Linear Models applied to Power Quality Disturbance Classification

, 2015
Power quality (PQ) analysis describes the non-pure electric signals that are usually present in electric power systems. The automatic recognition of PQ disturbances can be seen as a pattern recognition problem, in which different types of waveform ...
López-Lopera, Andrés F., Orozco, Ávaro A., Álvarez, Mauricio A.   +2 more
core   +1 more source

A Model-Free Deep Reinforcement Learning-Based Approach for Assessment of Real-Time PV Hosting Capacity

Energies
Assessments of the hosting capacity of electricity distribution networks are of paramount importance, as they facilitate the seamless integration of rooftop photovoltaic systems into the grid, accelerating the transition towards a more carbon neutral and
Jude Suchithra, Duane A. Robinson, Amin Rajabi   +2 more
doaj   +1 more source

Data mining for classification of power quality problems using WEKA and the effect of attributes on classification accuracy

Protection and Control of Modern Power Systems, 2018
There is growing interest in power quality issues due to wider developments in power delivery engineering. In order to maintain good power quality, it is necessary to detect and monitor power quality problems.
S. Asha Kiranmai, A. Jaya Laxmi
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Evaluation of Power Quality in Off-Grid Power System

Communications, 2015
The energy independence, reliability and safety of energy distribution system operation as well as use of renewable resources have been hot research topics in recent years. This research leads to the development of active distribution grids with specific
Stanislav Misak, Lukas Prokop, Petr Bilik, Petr Krejci   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Low Power Resonant Optical Excitation of an Optomechanical Cavity

, 2010
We demonstrate the actuation of a double beam opto-mechanical cavity with a sinusoidally varying optical input power. We observe the driven mechanical motion with only 200 nW coupled to the optical cavity mode.
Altug, Arka Majumdar, Armand Rundquist, Eichenfield, Eichenfield, Eichenfield, Englund, Jelena Vučković, Kippenberg, Kippenberg, Kippenberg, Li, Li, Notomi, Pernice, Povinelli, Povinelli, Quan, Roels, Safavi-Naeini, Schliesser, Van Thourhout, Wiederhecker, Yiyang Gong   +23 more
core   +1 more source

A Multi-Functional Reactive Power Compensation Device with the Capability of Grounding Fault Regulation and Its Parameter Design Method

Energies
Aiming at the problems of low equipment utilization and the high-capacity requirements of existing arc-suppression devices, a multi-functional reactive power compensation device with the capability of grounding fault regulation (MF-RPCD) is proposed ...
Zejun Huang, Yuchao Hou, Huaying Zhang, Huicong Liu, Xiaorui Liang, Qi Guo   +5 more
doaj   +1 more source