Results 71 to 80 of about 12,415,098 (263)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Identification method of all-operating-point admittance model for wind farms considering frequency-coupling characteristics

International Journal of Electrical Power & Energy Systems
Admittance identification is an effective tool to solve the issue of black-box admittance modeling in wind farms. However, due to the large operating range of wind farms, it is difficult to accurately identify the admittance model of wind farms under all
Zilin Zhang, Wenhua Wu, Zhiwei Xie, Yandong Chen, Yuancan Xu, Shixiang Cao, Zhihao Dai   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

ROCOV scheme for Fault Detection and Location in HVDC sytems [PDF]

, 2019
Publisher Copyright: © 2019, European Association for the Development of Renewable Energy, Environment and Power Quality (EA4EPQ). All rights reserved.A reliable DC fault protection system is essential for the development of HVDC grids.
Rubio, A., Larruskain, D.M., Abarrategi, O., Perez-Basante, A., Díaz, J.   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Minimization of Load Variance in Power Grids—Investigation on Optimal Vehicle-to-Grid Scheduling

Energies, 2017
The introduction of electric vehicles into the transportation sector helps reduce global warming and carbon emissions. The interaction between electric vehicles and the power grid has spurred the emergence of a smart grid technology, denoted as vehicle ...
Kang Miao Tan, Vigna K. Ramachandaramurthy, Jia Ying Yong, Sanjeevikumar Padmanaban, Lucian Mihet-Popa, Frede Blaabjerg   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A NOVEL THEORY OF REFERENCE REACTIVE CURRENT IDENTIFICATION BASED ON THE PER UNIT SYSTEM USED FOR THE ACTIVE FILTERS

Electrica, 2008
This paper, presents a new method of reactive current identification. The principle is based on the transformation of the voltage and current of the electrical supply network to the per unit system.
O. ABDELKHALEK, C. BENACHAIBA, T. BENSLIMANE, M. HAIDAS   +3 more
doaj   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

People’s livelihood demand prediction based on improved generative adversarial networks and reinforcement learning

Journal of Information and Telecommunication
At present, people's livelihood demand data collection is often affected by factors such as limited geographical coverage, a high proportion of sudden demands, and inconsistent data recording periods.
Xiaojun Ding, Yanxin Luo, Chaoqun Tuo, Jun Gao   +3 more
doaj   +1 more source