Results 111 to 120 of about 5,629,230 (293)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

An improved grid-forming control method with adaptive virtual impedance combining current limitation and transient stability improvement

International Journal of Electrical Power & Energy Systems
The virtual impedance (VI) control method is widely used to limit fault current for grid-forming converter (GFMC). However, in this article, it is found that the VI deteriorates the transient synchronization stability of the GFMC under grid faults.
Xiaoping Zhou, Lei Zhang, Hanting Peng, Lerong Hong, Qianming Xu, Zhen Zhang, Jiakun Shao, Jianchao Ma, Yizhen Hu   +8 more
doaj   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Power quality improvement using unified power quality conditioner [PDF]

, 2019
In this thesis, the applications of Artificial Neural Network (ANN) techniques as controllers for the shunt active filter and Unified Power Quality Conditioner (UPQC) are proposed. The research in this thesis includes building up the conventional shunt active filter and UPQC from scratch using analogue electronic components.
openaire   +2 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Multi-Source Information Fusion for Environmental Perception of Intelligent Vehicles Using Sage-Husa Adaptive Extended Kalman Filtering

Sensors
With the rapid advancement of intelligent driving technology, multi-source information fusion has become a vital topic in the field of environmental perception.
Yibo Meng, Huifang Kong, Tiankuo Liu
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Development of D-Statcom in hardware in the loop system for voltage SAG mitigation [PDF]

, 2019
The problem of power quality (PQ) is of utmost concern today. The widespread use of electronic equipment such as adjustable speed drive (ASD), programmable logic controller (PLC), information technology equipment in power electronics applications such
Mohammed, Amjad Muneim
core  

A cooperative control strategy for power quality based on parallel grid-connected converters

电力工程技术
Power quality control based on grid-connected converter can effectively utilize the surplus capacity of the converter and improves the benefits. However, existing methods tend to only consider grid-following (GFL) control and fail to fully utilize the ...
LIANG Xiaorui, LUO Yuhang, ZHANG Huaying, TU Chunming, LIU Huicong, ZHENG Yuting   +5 more
doaj   +1 more source