Results 61 to 70 of about 6,378 (166)

What has been researched about monkeypox? a bibliometric analysis of an old zoonotic virus causing global concern

New Microbes and New Infections, 2022
Alfonso J. Rodríguez-Morales, Yeimer Ortiz-Martínez, D. Katterine Bonilla-Aldana   +2 more
doaj   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Mpox Outbreak in the East Africa Region: Current Status, Containment Measures, Challenges, and Future Direction

Public Health Challenges, Volume 5, Issue 1, March 2026.
The WHO declares the Mpox outbreak a Public Health Emergency of International Concern, with the DRC as the epicenter in the EAC. DRC, Uganda, and Burundi experience extensive transmission; Kenya and Uganda show higher case fatality rates. Containment measures include surveillance, public awareness, infection prevention training, and vaccination (>73 ...
Reuben Sindayiheba, Noel Gahamanyi, Jerome Ndayisenga, Edouard Ntagwabira, Emmanuel Nsengiyumva, Emmanuel Kabalisa, Gashegu Misbah, Isabelle Mukagatare, Leon Mutesa, Claude Mambo Muvunyi   +9 more
wiley   +1 more source

Sexually transmitted monkeypox with pseudo-koebnerization within a tattoo

JAAD Case Reports, 2023
Nadav Friedel, MD, Elisa S. Gallo, MD, Tamir Horovitz, MD, Ronen Ben Ami, MD, Eli Sprecher, MD, PhD, MBA   +4 more
doaj   +1 more source

An mRNA Vaccine Based on Antigens From Conserved Regions of Monkeypox Virus A35R and M1R With a Dimer‐Like Conformation Confers Protection Against Both Monkeypox Virus and Vaccinia Virus Infections in Mice

MedComm, Volume 7, Issue 2, February 2026.
We developed four candidate mRNA vaccine antigens based on conserved sequences of MPXV A35R and M1R proteins. Our findings demonstrate that the MV2 vaccine possesses favorable immunogenicity and prophylactic potential against MPXV and VACV infections, positioning it as a promising clinical candidate for MPXV prevention.
Cong Tang, Longhai Yuan, Yun Xie, Yun Yang, Yanan Zhou, Junbing Wang, Hao Yang, Rui Peng, Jiali Xu, Wenhai Yu, Qing Huang, Wenqi Quan, Baisheng Li, Youchun Wang, Shuaiyao Lu   +14 more
wiley   +1 more source

Culture du virus claveleux sur cellules : application à la vaccination et au contrôle de l'immunité

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1978
Dans cette publication sont étudiées quelques propriétés du virus claveleux cultivé sur cellules in vitro: E. C.
J. Ramisse, J. Asso, A. Hassani, O. Anane, J. Jemli   +4 more
doaj   +1 more source

Orthopoxvirus Genome Evolution: The Role of Gene Loss

Viruses, 2010
Poxviruses are highly successful pathogens, known to infect a variety of hosts. The family Poxviridae includes Variola virus, the causative agent of smallpox, which has been eradicated as a public health threat but could potentially reemerge as a ...
Eneida L. Hatcher, Elliot J. Lefkowitz, Robert Curtis Hendrickson, Chunlin Wang   +3 more
doaj   +1 more source

Parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cells

Journal of Veterinary Research, 2016
Introduction: Orf virus (ORFV) is a prototype Parapoxvirus species in the Poxviridae family that causes serious zoonotic infectious disease. Goat skin fibroblast (GSF) cells are the major host targets of ORFV.
Wang Lingling, Lu Bingzhou, Zheng Haixue, Zhang Keshan, Liu Xiangtao   +4 more
doaj   +1 more source

Pox virose chez le mouton mauritanien. Clavelée ou maladie nodulaire atypiques ?

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1985
A la faveur de la sécheresse, des moutons mauritaniens ont développé des troubles cutanés et généraux catalogués traditionnellement "clavelée".
G. Chamoiseau
doaj   +1 more source

PoxiPred: An Artificial-Intelligence-Based Method for the Prediction of Potential Antigens and Epitopes to Accelerate Vaccine Development Efforts against Poxviruses

Biology
Poxviridae is a family of large, complex, enveloped, and double-stranded DNA viruses. The members of this family are ubiquitous and well known to cause contagious diseases in humans and other types of animals as well. Taxonomically, the poxviridae family
Gustavo Sganzerla Martinez, Mansi Dutt, David J. Kelvin, Anuj Kumar   +3 more
doaj   +1 more source