Results 101 to 110 of about 9,912 (196)
Poxviruses are large enveloped viruses that replicate exclusively in the cytoplasm. Like all viruses, their replication cycle begins with virion adsorption to the cell surface.
Erica B Flores +2 more
core +1 more source
Using purine skews to predict genes in AT-rich poxviruses
Background Clusters or runs of purines on the mRNA synonymous strand have been found in many different organisms including orthopoxviruses. The purine bias that is exhibited by these clusters can be observed using a purine skew and in the case of ...
Upton Chris, Da Silva Melissa
core +1 more source
Molecular characterization of poxviruses associated with tattoo skin lesions in UK cetaceans.
There is increasing concern for the well-being of cetacean populations around the UK. Tattoo skin disease (characterised by irregular, grey, black or yellowish, stippled cutaneous lesions) caused by poxvirus infection is a potential health indicatora ...
Sabine Tippelt +6 more
core +1 more source
Poxin-deficient poxviruses are sensed by cGAS prior to genome replication [PDF]
Poxviruses are dsDNA viruses infecting a wide range of cell types, where they need to contend with multiple host antiviral pathways, including DNA and RNA sensing.
Eke, Lucy +7 more
core +1 more source
Hypermethylated in cancer, a new candidate tumor suppressor gene located in 17p13.3, encodes a protein with five Krüppel-like C2H2 zinc finger motifs and a N-terminal protein/protein interaction domain called broad complex, tramtrack and bric à brac ...
Sophie Deltour +5 more
core +1 more source
Molecular Dating in the Evolution of Vertebrate Poxviruses
<i>Objectives:</i> The goal of this work was to study the evolutionary history of the vertebrate poxviruses using the Bayesian relaxed clock and a large set of highly conserved vitally important viral genes.
Irina N. Babkina, Igor V. Babkin
core +1 more source
The genome of the genus B entomopoxvirus from Amsacta moorei (AmEPV) was sequenced and found to contain 232,392 bases with 279 unique open reading frames (ORFs) of greater than 60 amino acids. The central core of the viral chromosome is flanked by 9.4-kb
Farmerie, William +5 more
core +1 more source
Innate immune activation of NFκB and its antagonism by poxviruses
In recent years there has been an acceleration of discovery in the field of innate anti-viral immunity to the point that many of the key events in early virus sensing and the discrete anti-viral responses they trigger have been elucidated in detail.
Bowie, Andrew, Brady, Gareth
core
Background Poxviruses are important pathogens of humans, livestock and wild animals. These large dsDNA viruses have a set of core orthologs whose gene order is extremely well conserved throughout poxvirus genera.
Aoife McLysaght +3 more
core +1 more source

