Results 81 to 90 of about 10,656 (197)
TNF Decoy Receptors Encoded by Poxviruses
, 2021 Tumour necrosis factor (TNF) is an inflammatory cytokine produced in response to viral infections that promotes the recruitment and activation of leukocytes to sites of infection.
Álvarez-de Miranda, Francisco J. +7 more
core +1 more source
Status and future of recombinant adeno‐associated virus vector manufacturing
Biotechnology Progress, Volume 42, Issue 5, September/October 2026.Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Molecular diagnostics by PCR of poxviruses (Orthopoxvirus (OPV) and Molluscum contagiosum virus (MCV)) in Cote d'Ivoire West Africa [PDF]
, 2017 The Orthopoxvirus (OPV) and the Molluscum contagiosum virus (MCV) are Poxviruses involved in viruses skin lesions in humans. OPV infects many vertebrates and MCV mainly infects humans. A diagnostic confusion is often observed between the clinical lesions
Meite, S +11 more
core +1 more source
Hematological Oncology, Volume 44, Issue 5, September 2026.ABSTRACT BCL6 is a master transcriptional regulator of germinal center (GC) B cells. BCL6 is frequently translocated at the major translocation cluster (MTC) within intron 1 of the BCL6 locus, a hotspot commonly rearranged in diffuse large B cell lymphomas (DLBCLs).
Santosh Kumar Gothwal +4 more
wiley +1 more source
Poxviruses Taking a Ride on Actin: New Users of Known Hardware
, 2009 Vaccinia virus uses A36 to recruit the actin polymerization effectors Nck and N-WASP to drive actin tail formation. Now, Dodding and Way identify functional orthologs of A36 in other vertebrate poxviruses that harbor varying numbers of Nck-binding sites ...
Rottner, Klemens, Stradal, Theresia E.B.
core +1 more source
The bioinformatic characterization of five novel poxviruses
, 2018 Poxviruses are double stranded (ds) DNA viruses with large brick-shaped virions (~200x300nm) that can be seen by light microscopy. The Chordopoxvirus (ChPV) subfamily demonstrates a vast genetic diversity in poxvirus virulence and evolution, and infects ...
Tu, Shin-Lin (Cindy)
core
, 2020 Poxviruses are large enveloped viruses that replicate exclusively in the cytoplasm. Like all viruses, their replication cycle begins with virion adsorption to the cell surface.
Erica B Flores +2 more
core +1 more source
Genome Variability and Gene Content in Chordopoxviruses: Dependence on Microsatellites
Viruses, 2015 To investigate gene loss in poxviruses belonging to the Chordopoxvirinae subfamily, we assessed the gene content of representative members of the subfamily, and determined whether individual genes present in each genome were intact, truncated, or ...
Eneida L. Hatcher +2 more
doaj +1 more source
Genetic screen of a library of chimeric poxviruses identifies an ankyrin repeat protein involved in resistance to the avian type I interferon response. [PDF]
, 2013 Viruses must be able to resist host innate responses, especially the type I interferon (IFN) response. They do so by preventing the induction or activity of IFN and/or by resisting the antiviral effectors that it induces.
Ross, C +5 more
core +1 more source
VirusesProtein kinase R (PKR) is an antiviral protein that is involved in molecular “arms races” with viral antagonists. As a result, some PKR inhibitors, including the vaccinia virus (VACV) protein K3 and its orthologs from other poxviruses only inhibit PKRs ...
Chorong Park +6 more
doaj +1 more source