Results 61 to 70 of about 10,498 (172)
Virulent poxviruses inhibit DNA sensing by preventing STING activation [PDF]
, 2018 Cytosolic recognition of DNA has emerged as a critical cellular mechanism of host immune activation upon pathogen invasion. The central cytosolic DNA sensor cGAS activates STING, which is phosphorylated, dimerises and translocates from the ER to a ...
Carlos Maluquer de Motes +11 more
core +2 more sources
Identification from diverse mammalian poxviruses of host-range regulatory genes functioning equivalently to vaccinia virus C7L [PDF]
, 2008 Vaccinia virus (VACV) C7L is a host-range gene that regulates cellular tropism of VACV. Distantly related C7L homologues are encoded by nearly all mammalian poxviruses, but whether they are host-range genes functioning similar to VACV C7L has not been ...
Xiang, Yan, Chao, Jie, Meng, Xiangzhi
core +1 more source
A novel and sensitive real-time PCR system for universal detection of poxviruses
, 2021 An Author Correction to this article was published on 08 April 2022: https://www.nature.com/articles/s41598-022-09876-5International audienceSuccess in smallpox eradication was enabled by the absence of non-human reservoir for smallpox virus.
Luciani, Léa +9 more
core +1 more source
Nck- and N-WASP-Dependent Actin-Based Motility Is Conserved in Divergent Vertebrate Poxviruses [PDF]
, 2009 SummaryVaccinia virus enhances its cell-to-cell spread by stimulating actin polymerization via Src- and Abl-mediated phosphorylation of the highly conserved orthopoxvirus protein A36.
Dodding, Mark P. +3 more
core +1 more source
Serp2, an inhibitor of the interleukin-1beta-converting enzyme, is critical in the pathobiology of myxoma virus [PDF]
, 1998 Recently, myxoma virus was shown to encode an additional member of the serpin superfamily. The viral gene, called serp2, was cloned, and the Serp2 protein was shown to specifically bind to interleukin-1beta (IL-1beta)-converting enzyme (ICE), thus ...
Messud-Petit, Frédérique +6 more
core
, 2016 Recombinant poxviruses are important tools for research and some are candidate vaccines. To make these viruses a simple, small vector that can be used to engineer multiple strains of vaccinia virus and other model poxviruses, including ectromelia virus ...
Smith, Stewart +4 more
core +1 more source
, 2022 Raw data for figures corresponding to the publication "A strategy to suppress STAT1 signalling conserved in pathogenic poxviruses and paramyxoviruses".THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Talbot-Cooper, C (via Mendeley Data)
core +1 more source
Zoonotic Poxviruses Associated with Companion Animals
, 2011 Understanding the zoonotic risk posed by poxviruses in companion animals is important for protecting both human and animal health. The outbreak of monkeypox in the United States, as well as current reports of cowpox in Europe, point to the fact that ...
Mary G. Reynolds, Danielle M. Tack
core +1 more source
Genome Variability and Gene Content in Chordopoxviruses: Dependence on Microsatellites
Viruses, 2015 To investigate gene loss in poxviruses belonging to the Chordopoxvirinae subfamily, we assessed the gene content of representative members of the subfamily, and determined whether individual genes present in each genome were intact, truncated, or ...
Eneida L. Hatcher +2 more
doaj +1 more source
Poxviruses Taking a Ride on Actin: New Users of Known Hardware [PDF]
, 2009 Vaccinia virus uses A36 to recruit the actin polymerization effectors Nck and N-WASP to drive actin tail formation. Now, Dodding and Way identify functional orthologs of A36 in other vertebrate poxviruses that harbor varying numbers of Nck-binding sites ...
Rottner, Klemens, Stradal, Theresia E.B.
core +1 more source