Results 51 to 60 of about 10,656 (197)

Investigation of the Efficacy and Safety of TO‐208 in Patients 2 Years of Age or Older With Molluscum Contagiosum in Japan: A Randomized, Double‐Blind, Placebo‐Controlled, Phase 3 Study (208‐3‐1) and Its Open‐Label Extension

The Journal of Dermatology, EarlyView.
ABSTRACT Molluscum contagiosum (MC) is a common viral skin infection in children. In the two Phase 3 Cantharidin Application in Molluscum Patients [CAMP‐1 and CAMP‐2] studies, cantharidin, a drug‐device combination containing cantharidin (0.7%), a topical vesicant, was significantly superior to placebo in achieving complete clearance of MC lesions at ...
Takafumi Kadono, Tsuyoshi Mitsuishi, Akira Shimizu, Yasushi Suga, Daisuke Watanabe, Shinya Kaneko, Ryota Ishiwata, Thomas F. Haws, Susan Cutler, Atsuyuki Igarashi   +9 more
wiley   +1 more source

Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling (Raw Data)

, 2022
Raw data for figures corresponding to the publication "A strategy to suppress STAT1 signalling conserved in pathogenic poxviruses and paramyxoviruses".THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Talbot-Cooper, C (via Mendeley Data), Talbot-Cooper, Callum   +1 more
core   +1 more source

The First Report of Cod Gill Poxvirus in Gills of Atlantic Cod (Gadus morhua L.) Suffering From Cardiorespiratory Disease

Journal of Fish Diseases, Volume 48, Issue 4, April 2025.
ABSTRACT Atlantic cod farming experiences renewed growth in Norway, and increased awareness is essential to address emerging diseases in this species. There are few reports on gill diseases in cod, and to date, no viral gill infections of cod have been documented. In this study, we collected samples from three sequential time points in summer 2023 from
Mona C. Gjessing, Torstein Tengs, Hanne Nilsen, Saima Mohammad, Simon C. Weli   +4 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Stress Beyond Translation: Poxviruses and More

, 2016
Poxviruses are large double-stranded DNA viruses that form viral factories in the cytoplasm of host cells. These viruses encode their own transcription machinery, but rely on host translation for protein synthesis. Thus, poxviruses have to cope with and,
Jason Liem, Jia Liu
core   +1 more source

Identification of multiple independent horizontal gene transfers into poxviruses using a comparative genomics approach [PDF]

, 2008
Background Poxviruses are important pathogens of humans, livestock and wild animals. These large dsDNA viruses have a set of core orthologs whose gene order is extremely well conserved throughout poxvirus genera.
Aoife McLysaght, Bratke Kirsten A, McLysaght Aoife, Kirsten A Bratke   +3 more
core   +2 more sources

Poxvirus K3 Orthologs Regulate NF-κB-Dependent Inflammatory Responses by Targeting the PKR–eIF2α Axis in Multiple Species

Vaccines
Background: Protein kinase R (PKR) inhibits general mRNA translation by phosphorylating the alpha subunit of eukaryotic translation initiation factor 2 (eIF2).
Huibin Yu, Mary Eloise L. Fernandez, Chen Peng, Dewi Megawati, Greg Brennan, Loubna Tazi, Stefan Rothenburg   +6 more
doaj   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, Volume 13, Issue 61, 3 November 2026.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Adventures with Poxviruses of Vertebrates

, 2015
Because they were the largest of all viruses and could be visualised with a light microscope, the poxviruses were the first viruses to be intensively studied in the laboratory.
Fenner, Frank
core   +1 more source

The Global Health Threat of Monkeypox Virus: Understanding Its Biology, Transmission, and Potential Therapeutic Interventions

Infection and Drug Resistance, 2023
Yan He,1,* Ying Tang,2,* Caiyun Wang,3 Zilie Zhou,3 Wei Li,4 Man Tian3 1Department of Infection Management, Nanjing Drum Tower Hospital, Nanjing, Jiangsu, People’s Republic of China; 2Department of Ultrasound Diagnostic, Children’s Hospital of ...
He Y, Tang Y, Wang C, Zhou Z, Li W, Tian M   +5 more
doaj