Nuclear localization of the human cytomegalovirus tegument protein pp150 (ppUL32)
The human cytomegalovirus (HCMV) basic phosphoprotein pp150, encoded by the UL32 gene, together with the two other major phosphoproteins, pp65 (ppUL83) and pp71 (ppUL82) and several minor structural proteins, form the tegument around the viral nucleocapsid.
G, Hensel +4 more
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Human cytomegalovirus infection of langerhans-type dendritic cells does not require the presence of the gH/gL/UL128-131A complex and is blocked after nuclear deposition of viral genomes in immature cells [PDF]
Human cytomegalovirus (CMV) enters its host via the oral and genital mucosae. Langerhans-type dendritic cells (LC) are the most abundant innate immune cells at these sites, where they constitute a first line of defense against a variety of pathogens.
A. R. Fehr +111 more
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PDGF Receptor-α Does Not Promote HCMV Entry into Epithelial and Endothelial Cells but Increased Quantities Stimulate Entry by an Abnormal Pathway [PDF]
Epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor-α (PDGFRα) were reported to mediate entry of HCMV, including HCMV lab strain AD169.
Johnson, David C. +4 more
core +2 more sources
Bicaudal D1-Dependent Trafficking of Human Cytomegalovirus Tegument Protein pp150 in Virus-Infected Cells [PDF]
ABSTRACT Human cytomegalovirus (HCMV) virion assembly takes place in the nucleus and cytoplasm of infected cells. The HCMV virion tegument protein pp150 (ppUL32) is an essential protein of HCMV and has been suggested to play a role in the cytoplasmic phase of HCMV assembly.
Sabarish V, Indran +2 more
openaire +2 more sources
Age-related macular degeneration (AMD) and central serous chorioretinopathy (CSC) are diseases targeting the posterior segment of the eye that often lead to lowered visual functions. Pathogenesis of such disorders largely remains unclear.
V. V. Neroev +7 more
doaj +1 more source
Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]
Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Berencsi, Klára +11 more
core +1 more source
مسؤولية الدولة تجاه تحسين الأوضاع الاقتصادية
المسؤولية هي التي تجعل الإنسان، كائنا حركياً ومنهجياً، دائباً على الطريق وصولاً إلى آماله وغاياته الوجودية والكونية وهي الأمانة التي بها تنظم أمور الحياة والآخرة هي المسؤولية التي تسهل الصعوبات، وتزيل الظلمات، و تيسير الاستقامة على السبل والطرقات، وتخفف ...
Hemin A. Braiem
doaj +1 more source
The ZupT transporter plays an important role in zinc homeostasis and contributes to Salmonella enterica virulence [PDF]
Zinc is an essential metal for cellular homeostasis and function in both eukaryotes and prokaryotes. To acquire this essential nutrient, bacteria employ transporters characterized by different affinity for the metal. Several studies have investigated the
Ammendola, S +8 more
core +1 more source
The entire amino acid sequence of human cytomegalo-virus (HCMV) 150K matrix phosphoprotein (pp150), consisting of 1048 amino acid residues, was divided into 95 overlapping 20 amino acid peptides which were synthesized on polyethylene rods. The rods were subjected to ELISA with pooled anti-HCMV-positive and anti-HCMV-negative sera.
J, Novák +5 more
openaire +2 more sources
Changing the Rules of the Game: The Impact of Privatization on Firm Industrial Relations [PDF]
This paper examines the impact of privatization on the relative bargaining strength of management and trade unions. Findings are based on a study of Ireland’s largest telecoms provider, Eircom, which has been privatized since 1999.
McCarthy, Dermot +2 more
core +1 more source

