Results 11 to 20 of about 816 (161)

Cytomegalovirus pUL96 Is Critical for the Stability of pp150-Associated Nucleocapsids [PDF]

Journal of Virology, 2011
Maturation of human cytomegalovirus (HCMV) initiates with nucleocapsids that egress from the nucleus and associate with a juxtanuclear cytoplasmic assembly compartment, where virion envelopment and release are orchestrated.
Ritesh Tandon
exaly   +4 more sources

Effect of Cytomegalovirus Recombinant Phosphoprotein 150 (pp150) on Function and Maturation of Murine Dendritic Cells: an In-Vitro Study [PDF]

Iranian Journal of Immunology, 2020
Background: Tegument protein pp150 of cytomegaloviruses (CMVs) plays a vital role in all stages of viral life cycle, representing the most important tegument protein candidate for HCMV treatment.
Yousef Nikmanesh, Shohreh Shahmahmoodi, Ramin Yaghobi, Sayed Mahdi Marashi, Mahmood Mahmoudi, Mahdokht Hossein Aghdaie, Maryam Khosravi, Mohammad Hossein Karimi   +7 more
doaj   +3 more sources

Highly quantitative serological detection of anti-cytomegalovirus (CMV) antibodies [PDF]

Virology Journal, 2009
Background Human cytomegalovirus infection is associated with a variety of pathological conditions including retinitis, pneumonia, hepatitis and encephalitis that may be transmitted congenitally, horizontally and parenterally and occurs both as a primary
Alter Harvey J, Drew W Lawrence, Exner Maurice, Ching Kathryn H, Issa Alexandra T, Burbelo Peter D, Iadarola Michael J   +6 more
doaj   +2 more sources

Prepandemic levels of cytokines and immunoglobulins and risk of SARS-CoV-2 infection and COVID-19 in the general population of Barcelona [PDF]

Frontiers in Public Health
BackgroundFrom a public health perspective it is remarkable that there are yet no longitudinal studies in the general population investigating the influence of the basal immune state, measured before the pandemic, on the risk of SARS-CoV-2 infection and ...
Miquel Porta, Miquel Porta, Miquel Porta, Miquel Porta, Miquel Porta, Miquel Porta, José Pumarega, José Pumarega, José Pumarega, Ruth Aguilar, Ruth Aguilar, David Prieto-Merino, Laura Campi, Laura Campi, Cristina Rius, Cristina Rius, Cristina Rius, Judit Villar-García, Marta Vidal, Marta Vidal, Marta Vidal, Alfons Jimenez, Alfons Jimenez, Alfons Jimenez, Antonio Peña, Miguel-Ángel Muñoz, Miguel-Ángel Muñoz, Leonardo Trasande, Leonardo Trasande, Leonardo Trasande, Francisco Bolúmar, Francisco Bolúmar, Gemma Moncunill, Gemma Moncunill, Gemma Moncunill, Magda Gasull, Magda Gasull, Magda Gasull, Carlota Dobaño, Carlota Dobaño, Carlota Dobaño   +40 more
doaj   +2 more sources

Optimized multi-epitope neoantigen human cytomegalovirus vaccine based on adenovirus vectors elicits potent antiviral immunity [PDF]

Frontiers in Immunology
IntroductionHuman cytomegalovirus (HCMV) induces severe morbidity and mortality in neonates, organ transplant recipients, and immunocompromised individuals. Currently, there is no licensed vaccine for HCMV.
Shasha Jiang, Shasha Jiang, Xianjuan Zhang, Heping Zhao, Fengjun Liu, Fengjun Liu, Zonghui Li, Zonghui Li, Xiaoli Yang, Xiaoli Yang, Wenxuan Liu, Jing Lv, Yi Zhang, Yiran Zhang, Yan Yu, Bin Wang, Yunyang Wang   +16 more
doaj   +2 more sources

Identification of a human cytomegalovirus mutant in the pp150 matrix phosphoprotein gene with a growth-defective phenotype

Journal of General Virology, 1993
Following amplification by PCR of a portion of the matrix phosphoprotein pp150 gene, electrophoretic analysis revealed the simultaneous presence of two viral variants of human cytomegalovirus in the blood of a heart transplant recipient.
Zipeto D., Percivalle E., Gerna G., Milanesi G., Baldanti F.   +4 more
core   +4 more sources

Cytotoxic T Lymphocyte (CTL) Responses to Human Cytomegalovirus pp65, IE1‐Exon4, gB, pp150, and pp28 in Healthy Individuals: Reevaluation of Prevalence of IE1‐Specific CTLs

Journal of Infectious Diseases, 2000
The prevalence of human cytomegalovirus (HCMV) pp65-, pp150-, IE1-exon4–, gB- and pp28-specific cytotoxic T lymphocyte (CTL) responses was compared among 34 healthy individuals, grouped by neutralizing antibody titers.Moderately and highly seropositive ...
Katalin Burian, William I Cox, Klara Berencsi   +2 more
exaly   +1 more source

Human cytomegalovirus tegument protein pp150 acts as a cyclin A2–CDK-dependent sensor of the host cell cycle and differentiation state [PDF]

Proceedings of the National Academy of Sciences, 2013
Significance Depending on the host cell type and differentiation status, herpesviruses establish different modes of infection to either maintain or replicate their genomes.
Winkler, Michael, Bogdanow, Boris, Hagemeier, Christian, von Einem, Jens, Straschewski, Sarah, Weisbach, Henry, Voigt, Sebastian, Wiebusch, Lüder   +7 more
core   +4 more sources

Predictive value of gB2 antibodies for maternal-fetal transmission after primary cytomegalovirus infection treated with valacyclovir. [PDF]

Ultrasound Obstet Gynecol
ABSTRACT Objective To estimate the residual risk of maternal–fetal transmission after primary cytomegalovirus (CMV) infection in the periconceptional period or the first trimester in women treated with valacyclovir, and to assess whether the presence of glycoprotein B2 (gB2)‐specific immunoglobulin (Ig)‐G antibodies on immunoblot analysis refines fetal
Kagan KO, Bissinger AL, Roth O, Sonek J, Hoopmann M, Ville Y, Enders M.   +6 more
europepmc   +2 more sources

P706: RESISTANCE TO HYPOMETHYLATING AGENTS (HMA) IN HIGH-RISKMYELODYSPLASTIC SYNDROME (HR-MDS): THE ROLE OF THE ADENOSINEDEAMINASE ACTING ON RNA 1 (ADAR1) ENZYME [PDF]

Hemasphere, 2023
HemaSphere, Volume 7, Issue S3, August 2023.
Dimitriou D, Lamprianidou E, Tasis A, Spiropoulos T, Kimparidou C, Papadakis S, Liapis K, Papoutselis M, Vrachiolias G, Mitroulis I, Kotsianidis I.   +10 more
europepmc   +2 more sources