Predictive value of gB2 antibodies for maternal-fetal transmission after primary cytomegalovirus infection treated with valacyclovir. [PDF]
ABSTRACT Objective To estimate the residual risk of maternal–fetal transmission after primary cytomegalovirus (CMV) infection in the periconceptional period or the first trimester in women treated with valacyclovir, and to assess whether the presence of glycoprotein B2 (gB2)‐specific immunoglobulin (Ig)‐G antibodies on immunoblot analysis refines fetal
Kagan KO +6 more
europepmc +2 more sources
An Elastin-like Polypeptide-fusion peptide targeting capsid-tegument interface as an antiviral against cytomegalovirus infection [PDF]
The tegument protein pp150 of Human Cytomegalovirus (HCMV) is known to be essential for the final stages of virus maturation and mediates its functions by interacting with capsid proteins.
Komal Beeton +6 more
doaj +2 more sources
Prepandemic levels of cytokines and immunoglobulins and risk of SARS-CoV-2 infection and COVID-19 in the general population of Barcelona [PDF]
BackgroundFrom a public health perspective it is remarkable that there are yet no longitudinal studies in the general population investigating the influence of the basal immune state, measured before the pandemic, on the risk of SARS-CoV-2 infection and ...
Miquel Porta +40 more
doaj +2 more sources
Optimized multi-epitope neoantigen human cytomegalovirus vaccine based on adenovirus vectors elicits potent antiviral immunity [PDF]
IntroductionHuman cytomegalovirus (HCMV) induces severe morbidity and mortality in neonates, organ transplant recipients, and immunocompromised individuals. Currently, there is no licensed vaccine for HCMV.
Shasha Jiang +16 more
doaj +2 more sources
Highly quantitative serological detection of anti-cytomegalovirus (CMV) antibodies [PDF]
Background Human cytomegalovirus infection is associated with a variety of pathological conditions including retinitis, pneumonia, hepatitis and encephalitis that may be transmitted congenitally, horizontally and parenterally and occurs both as a primary
Alter Harvey J +6 more
doaj +3 more sources
Structure-guided mutagenesis targeting interactions between pp150 tegument protein and small capsid protein identify five lethal and two live-attenuated HCMV mutants [PDF]
Qiyi Tang +2 more
exaly +2 more sources
Effect of Cytomegalovirus Recombinant Phosphoprotein 150 (pp150) on Function and Maturation of Murine Dendritic Cells: an In-Vitro Study [PDF]
Background: Tegument protein pp150 of cytomegaloviruses (CMVs) plays a vital role in all stages of viral life cycle, representing the most important tegument protein candidate for HCMV treatment.
Yousef Nikmanesh +7 more
doaj +1 more source
Sequences for 2-Step BAC mutagenesis of HCMV-TB40-pp150-SNAP-gM-mScarlet-I. [PDF]
Sequences for 2-Step BAC mutagenesis of HCMV-TB40-pp150-SNAP-gM-mScarlet-I.
Timothy K. Soh (13199761) +9 more
core +1 more source
S9A and S9B HFF cells were infected with HCMV-TB40-pp150-SNAP-gM-mScarlet-I at an MOI of 2 and treated with the indicated substance at the indicated concentrations until 5 dpi. [PDF]
The medium containing the inhibitors was refreshed every 24 hours. 5 dpi cells were fixed, labeled with SNAP-Cell-SiR, and imaged by spinning-disk microscopy. White triangles indicate EVAs. Scale bars indicate 20 μm. S9C HFF cells were infected with HCMV-
Timothy K. Soh (13199761) +9 more
core +1 more source
Citrus Diseases Exotic to Florida: Witches' Broom Disease of Lime (WBDL)
This paper discusses Witches' Broom Disease of Lime (WBDL). This document is Fact Sheet PP-228, one of a series of the Plant Pathology Department, UF/IFAS Extension. Original publication date: April 2006.
Kuang Ren Chung +2 more
doaj +5 more sources

