Results 61 to 70 of about 14,919 (212)

Chemical Chaperone of Endoplasmic Reticulum Stress Inhibits Epithelial-Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium via the c-Src Pathway

open access: yesMediators of Inflammation, 2017
Epithelial-mesenchymal transition (EMT) is a biological process that allows epithelial cells to assume a mesenchymal cell phenotype. EMT is considered as a therapeutic target for several persistent inflammatory airway diseases related to tissue ...
Heung-Man Lee   +4 more
doaj   +1 more source

Functional morphology and biomechanics of the locomotor apparatus in the large Late Triassic carnivore Postosuchus kirkpatricki (Archosauria: Rauisuchidae)

open access: yesJournal of Anatomy, EarlyView.
A three‐dimensional model is used to analyze the locomotor biomechanics of the large Late Triassic archosaurian reptile Postosuchus kirkpatricki. The study finds that it is more uncertain than previously concluded whether it was quadrupedal or bipedal, and plantigrade or digitigrade, but it clearly had locomotor specializations including large hindlimb
John R. Hutchinson   +6 more
wiley   +1 more source

From Observations and Pictures to Images: Learning Lab@PP2 in Tourism Classes

open access: yesThe Qualitative Report, 2020
Learning Lab@PP2 is a pedagogical tool that has been applied in a degree course in tourism at the Polytechnic Institute of Beja, specifically in classes of Professional Practice II. It advocates that the learning process should occur in the complex context of society, organizations and professional relations that characterize the tourism industry.
Rodrigues, Ana Isabel, Amaral, Marta
openaire   +4 more sources

Agitation-dependent biomechanical forces modulate GPVI receptor expression and platelet adhesion capacity during storage

open access: yesThrombosis Journal, 2022
Background Continuous agitation during storage slows down the platelet storage lesions. However, in special circumstances, manual-mixing can be alternatively used to store products for short time periods without compromising platelet quality.
Ehteramolsadat Hosseini   +4 more
doaj   +1 more source

A functionally distinct HPA‐1a‐specific alloantibody associated with fetal/neonatal alloimmune thrombocytopenia that activates platelets via FcγRIIa

open access: yesTransfusion, EarlyView.
Abstract Background Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is caused by maternal alloantibodies directed against fetal platelet antigens, most commonly human platelet antigen‐1a (HPA‐1a). These antibodies mediate platelet destruction and can lead to fetal and neonatal thrombocytopenia severe enough to cause life‐threatening organ bleeds ...
Huiying Zhi   +9 more
wiley   +1 more source

Tamoxifen and Src kinase inhibitors as neuroprotective/neuroregenerative drugs after spinal cord injury

open access: yesNeural Regeneration Research, 2015
Spinal cord injury (SCI) is a devastating condition that produces significant changes in the lifestyle of patients. Many molecular and cellular events are triggered after the initial physical impact to the cord.
Iris K Salgado   +3 more
doaj   +1 more source

Real-Time Streaming Image Based PP2LFA-CRNN Model for Facial Sentiment Analysis

open access: yesIEEE Access, 2020
In modern society, the real-time emotion adaptive driving system for providing safety to drivers and emotion-based services are being researched. However, in the service process have problem of personal information might get leaked.
Chang-Min Kim   +4 more
doaj   +1 more source

The focal adhesion: a regulated component of aortic stiffness. [PDF]

open access: yesPLoS ONE, 2013
Increased aortic stiffness is an acknowledged predictor and cause of cardiovascular disease. The sources and mechanisms of vascular stiffness are not well understood, although the extracellular matrix (ECM) has been assumed to be a major component.
Robert J Saphirstein   +6 more
doaj   +1 more source

Clinical outcomes of a novel flowable calcium silicate cement in equine endodontic treatment

open access: yesEquine Veterinary Journal, Volume 58, Issue 6, Page 1602-1611, November 2026.
Abstract Background Orthograde endodontic treatment of equine cheek teeth is performed infrequently with variable success rates of obturation with calcium hydroxide paste (CHP). A novel flowable calcium silicate cement (eCSC) formulated for use as an obturation material in equine teeth has demonstrated acceptable canal filling volumes and evidence of ...
Kirsten Jackson   +5 more
wiley   +1 more source

Genetic Spectrum of Non‐PTPN11 Variants in Noonan Syndrome and Related RASopathies: Findings From a Russian Cohort

open access: yesClinical Genetics, Volume 110, Issue 5, Page 527-537, November 2026.
Noonan syndrome and related conditions are caused by variants in multiple genes. We analyzed 456 Russian patients using a 23‐gene panel and found disease‐causing variants in non‐PTPN11 genes in 85 cases. NF1, SOS1, BRAF, and SHOC2 explained half of these diagnoses.
Anna Orlova   +5 more
wiley   +1 more source

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