PPA2 activates MTFP1-DNM1L fission signaling to govern mitochondrial proliferation and mitophagy [PDF]
Gajanan Bhujangrao Kendre +2 more
exaly +2 more sources
A case of resuscitated cardiac arrest in a school-aged child with pyrophosphatase 2 deficiency [PDF]
William A. Harris, MD +3 more
doaj +2 more sources
Downregulation of PPA2 expression correlates with poor prognosis of kidney renal clear cell carcinoma [PDF]
Background Kidney renal clear cell carcinoma (KIRC) is the most common subtype of kidney cancer. Inorganic pyrophosphatase (PPA2) is an enzyme that catalyzes the hydrolysis of pyrophosphate to inorganic phosphate; few studies have reported its ...
Wenbiao Zhu +7 more
doaj +2 more sources
Nonischemic Cardiomyopathy in Adult-Onset PPA2-Deficient Mitochondrial Disease [PDF]
Thomas M Roston +2 more
exaly +2 more sources
Only one beer can be mortal: a case report of two sisters with cardiac arrest due to a homozygous mutation in PPA2 gene [PDF]
Manzanilla-Romero HH +3 more
exaly +2 more sources
Identification of Causal Genes of COVID-19 Using the SMR Method
Since the first report of COVID-19 in December 2019, more than 100 million people have been infected with SARS-CoV-2. Despite ongoing research, there is still limited knowledge about the genetic causes of COVID-19. To resolve this problem, we applied the
Yan Zong, Xiaofei Li
doaj +1 more source
The Effects of Pulsatilla Koreana NAKAI Pharmacopuncture Therapy on the Chunchu (ST25) for Dextran Sulfate Sodium-Induced Colitis in Mice [PDF]
Background This research was performed to investigate the effects of Pulsatilla Koreana NAKAI pharmacopuncture (PPA) therapy on intestinal disease in rats with dextran sulfate sodium (DSS)-induced colitis.
Tae Jun Yang +3 more
doaj +1 more source
Unexpected cases in field diagnosis of African swine fever virus in Vietnam: The needs consideration when performing molecular diagnostic tests [PDF]
Background: The first confirmed case of ASF in Vietnam was reported officially in February 2019. To date, ASF virus (ASFV) have been detected on 63/63 provinces in Vietnam.
Anh Duc Truong +10 more
doaj +1 more source
Causal Associations Between 4907 Circulating Proteins and Hyperlipidemia: A Two-Sample Mendelian Randomization Study Based on European Ancestry. [PDF]
ABSTRACT Background and Objective This study employed Mendelian randomization (MR) to investigate the causal relationships between 4907 circulating proteins and hyperlipidemia, with the aim of identifying potential drug targets. Methods Instrumental variables were derived from genome‐wide association study (GWAS) data on 4907 circulating proteins ...
Cheng H, Zhong D.
europepmc +2 more sources
The cytosolic level of inorganic pyrophosphate (PPi) is finely regulated, with PPi hydrolyzed primarily by the vacuolar H+-pyrophosphatase (H+-PPase, VHP1/FUGU5/AVP1) and secondarily by five cytosolic soluble pyrophosphatases (sPPases; PPa1–PPa5) in ...
Mayu Fukuda +9 more
doaj +1 more source

