Results 101 to 110 of about 5,154 (256)
Background Diabetic neuropathy is a common neuropathy associated with paresthaesia and pain. The mechanisms underlying the painful conditions are not well understood.
Xu Guang-Yin+3 more
doaj +1 more source
Characterisation of neurogenic lipolytic responses in white adipose tissue ex vivo
Background and Purpose Dysfunction of the autonomic nervous system is associated with cardiovascular dysfunction, including metabolic syndrome and obesity. Understanding mechanisms of neurogenic control of white adipose tissue is key to understanding adipose physiology and pathophysiology, though there is limited research exploring this in adipose ...
Kayleigh E. Goddard, Samuel J. Fountain
wiley +1 more source
Coordinated calcium signalling in cochlear sensory and non‐sensory cells refines afferent innervation of outer hair cells [PDF]
Outer hair cells (OHCs) are highly specialized sensory cells conferring the fine‐tuning and high sensitivity of the mammalian cochlea to acoustic stimuli.
Ceriani, Federico+11 more
core +2 more sources
TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate
Background and Purpose Abdominal pain is a leading cause of morbidity for people living with gastrointestinal disease. Whereas the transient receptor potential vanilloid 4 (TRPV4) ion channel has been implicated in the pathogenesis of abdominal pain, the relative paucity of TRPV4 expression in colon‐projecting sensory neurons suggests that non‐neuronal
Michelle Y. Meng+14 more
wiley +1 more source
Search for the end of a path in the d-dimensional grid and in other graphs [PDF]
We consider the worst-case query complexity of some variants of certain \cl{PPAD}-complete search problems. Suppose we are given a graph $G$ and a vertex $s \in V(G)$.
Gerbner, Dániel+4 more
core +2 more sources
Extracellular ATP (eATP) has been implicated in mediating plant growth and antioxidant defense; however, it is largely unknown whether eATP might mediate salinity tolerance.
Jian Sun+10 more
doaj +1 more source
Abstract Background Increasing evidence indicates that periodontitis contributes to systemic low‐grade inflammation. Porphyromonas gingivalis is strongly associated with periodontitis, and antibodies against the bacterium may be used as a serological proxy to account for periodontal status, when studying diseases associated with periodontitis.
Laura Massarenti+5 more
wiley +1 more source
Can PPAD Hardness be Based on Standard Cryptographic Assumptions?
We consider the question of whether PPAD hardness can be based on standard cryptographic assumptions, such as the existence of one-way functions or public-key encryption. This question is particularly well-motivated in light of new devastating attacks on obfuscation candidates and their underlying building blocks, which are currently the only known ...
Rosen, Alon, Segev, Gil, Shahaf, Ido
openaire +4 more sources
Role for astroglia-derived BDNF and MSK1 in homeostatic synaptic plasticity [PDF]
Homeostatic scaling of synaptic strength in response to environmental stimuli may underlie the beneficial effects of an active lifestyle on brain function.
Bogdanov, Alexander+4 more
core +1 more source
Therapeutic Controlled Release Strategies for Human Osteoarthritis
Therapeutic controlled release is a promising approach to treat the progressive and irreversible pathological changes in human osteoarthritis. This strategy is based on the application of recombinant molecules, drugs, and gene sequences via biocompatible materials and may provide effective and long‐lasting tools promoting the spatiotemporal delivery ...
Dan Wang+4 more
wiley +1 more source