Results 101 to 110 of about 5,261 (261)

P2X-Receptor Antagonists Inhibit the Interaction of S. aureus Hemolysin A with Membranes

Toxins, 2017
The pore forming hemolysin A, Hla, is a major virulence factor of Staphylococcus aureus. Apparently, 1–2 pore(s) per cell suffice(s) to cause cell death.
Markus Schwiering, Matthias Husmann, Nadja Hellmann   +2 more
doaj   +1 more source

The signaling role of extracellular ATP in co-culture of Shiraia sp. S9 and Pseudomonas fulva SB1 for enhancing hypocrellin A production

Microbial Cell Factories, 2021
Background Adenosine 5′-triphosphate (ATP) plays both a central role as an intracellular energy source, and a crucial extracellular signaling role in diverse physiological processes of animals and plants.
Xin Ping Li, Lu Lu Zhou, Yan Hua Guo, Jian Wen Wang   +3 more
doaj   +1 more source

P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential [PDF]

, 2012
P2Y receptors for extracellular nucleotides are coupled to activation of a variety of G proteins and stimulate diverse intracellular signaling pathways that regulate functions of cell types that comprise the central nervous system (CNS).
Erb, Laurie, Seye, Cheik I., Weisman, Gary A., Woods, Lucas T.   +3 more
core   +1 more source

Self‐Conscious Emotions in Technology Adoption: How Embarrassment and Shame Shape Consumer Responses to New Technologies

Psychology &Marketing, Volume 43, Issue 1, Page 108-129, January 2026.
ABSTRACT This article investigates how self‐conscious emotions, specifically embarrassment and shame, act as sequential emotional barriers that shape consumer behavior and hinder the adoption of multifunctional technologies. Drawing on theories of self‐conscious emotions and integrating them with established technology adoption models such as the ...
Edgar José Pereira Dias, Emílio José Montero Arruda Filho, Everaldo Marcelo Souza da Costa   +2 more
wiley   +1 more source

Mechanisms underlying purinergic P2X3 receptor-mediated mechanical allodynia induced in diabetic rats

Molecular Pain, 2011
Background Diabetic neuropathy is a common neuropathy associated with paresthaesia and pain. The mechanisms underlying the painful conditions are not well understood.
Xu Guang-Yin, Li Guangwen, Liu Ningang, Huang Li-Yen   +3 more
doaj   +1 more source

Role for astroglial α1-adrenoreceptors in gliotransmission and control of synaptic plasticity in the neocortex [PDF]

, 2015
Communication between neuronal and glial cells is thought to be very important for many brain functions. Acting via release of gliotransmitters, astrocytes can modulate synaptic strength.
Lalo, Ulyana, Pankratov, Yuriy
core   +2 more sources

OmpA_C‐Like Domain of PorE Is Essential for PorE Function in the Type IX Secretion System (T9SS) of Porphyromonas gingivalis and Some T9SS Cargo Proteins Are Secreted in a PorE‐Independent Manner

Microbiology and Immunology, Volume 70, Issue 1, Page 15-26, January 2026.
ABSTRACT The periodontal pathogen Porphyromonas gingivalis secretes gingipains, highly hydrolytic proteases, to the cell surface or external environment via a type IX secretion system (T9SS). PorE is one of the T9SS component proteins essential for gingipain secretion. It consists of four domains: TPR, WD40, CRD, and OmpA_C‐like.
Takashi Tominaga, Hideharu Yukitake, Paul D. Veith, Dhana G. Gorasia, Takao Ayuse, Takuro Sanuki, Eric C. Reynolds, Koji Nakayama, Mariko Naito, Mikio Shoji   +9 more
wiley   +1 more source

P2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH. [PDF]

, 2014
P2X receptors are commonly known as plasma membrane cation channels involved in a wide variety of cell functions. The properties of these channels have been extensively studied on the plasma membrane. However, studies in amoeba suggest that P2X receptors
Brailoiu, Burnstock, Calcraft, Chataigneau, Clarke, Dong, Dong, Dong, Dou, Fountain, Graves, Guo, Haanes, Hattori, Holtzman, Huynh, Kexin Zhao, Khakh, Lange, Lloyd-Evans, Michael X. Zhu, Miklavc, Mindell, Morgan, Nilsson, North, Pankratov, Parkinson, Patel, Peng Huang, Priel, Qi Cao, Qureshi, Royle, Ruth Murrell-Lagnado, Sawada, Silberberg, Sivaramakrishnan, Steinberg, Sumoza-Toledo, Xi Zoë Zhong, Xian-Ping Dong, Yuanjie Zou, Zalk, Zhang   +44 more
core   +2 more sources

Comparative genome analysis of tomato‐pathogenic Clavibacter michiganensis strains reveal genetic diversity in virulence genes

Annals of Applied Biology, Volume 188, Issue 1, Page 246-259, January 2026.
The present study builds upon this work, focusing on characterising the genomic diversity of Cmm strains exhibiting varying levels of pathogenicity in tomatoes. To this end, 12 Cmm strains displaying differential virulence on tomato were isolated and their genomes sequenced using the NovaSeq 6000 platform, using the reference Cmm strain PD223 as a ...
Huseyin Basim, Esin Basim, Huseyin Tombuloglu, Turgay Unver   +3 more
wiley   +1 more source

Extracellular ATP signaling is mediated by H₂O₂ and cytosolic Ca²⁺ in the salt response of Populus euphratica cells.

PLoS ONE, 2012
Extracellular ATP (eATP) has been implicated in mediating plant growth and antioxidant defense; however, it is largely unknown whether eATP might mediate salinity tolerance.
Jian Sun, Xuan Zhang, Shurong Deng, Chunlan Zhang, Meijuan Wang, Mingquan Ding, Rui Zhao, Xin Shen, Xiaoyang Zhou, Cunfu Lu, Shaoliang Chen   +10 more
doaj   +1 more source