Results 131 to 140 of about 5,154 (256)
Extracellular ATP activates NFAT-dependent gene expression in neuronal PC12 cells via P2X receptors
Background Treatment of neuronal PC12 cells with ATP induces depolarisation and increases intracellular calcium levels via purinergic receptors. In many cell types, sustained elevation of intracellular calcium levels cause changes in gene expression via ...
Becker Walter+2 more
doaj +1 more source
Emerging factors affecting peri‐implant bone metabolism
Abstract Implant dentistry has evolved to the point that standard implant osseointegration is predictable. This is attributed in part to the advancements in material sciences that have led toward improvements in implant surface technology and characteristics.
Angel Insua+4 more
wiley +1 more source
Abordagens frequentista e bayesiana para avaliação genética de bovinos da raça Canchim para características de crescimento. [PDF]
Este trabalho foi realizado com os objetivos de: a) comparar os componentes de (co)variância obtidos por meio dos métodos da Máxima Verossimilhança Restrita (REML) e da inferência bayesiana (IB); b) realizar a avaliação genética do peso à desmama (P240 ...
ALENCAR, M. M. de+2 more
core
P2Y11 receptors : properties, distribution and functions [PDF]
The P2Y11 receptor is a G protein-coupled receptor that is stimulated by endogenous purine nucleotides, particularly ATP. Amongst P2Y receptors it has several unique properties; 1) it is the only human P2Y receptor gene that contains an intron in the ...
Kennedy, Charles
core +1 more source
Skeletal Class III phenotype: Link between animal models and human genetics: A scoping review
Genetic variants associated with skeletal Class III malocclusion identified in animal models. Identified variants emphasize the role of BMP and TGF‐β signaling in bone growth and ossification regulation. Abstract This study aimed to identify evidence from animal studies examining genetic variants underlying maxillomandibular discrepancies resulting in ...
Alexandra Dehesa‐Santos+2 more
wiley +1 more source
P2X4 receptor function in the nervous system and current breakthroughs in pharmacology [PDF]
ATP is a well-known extracellular signalling molecule and neurotransmitter known to activate purinergic P2X receptors. Information has been elucidated about the structure and gating of P2X channels following the determination of the crystal structure of ...
Abdelrahman+174 more
core +2 more sources
Antidipsogenic effects of central adenosine-5'-triphosphate
Besides other physiological functions, adenosine-5'-triphosphate (ATP) is also a neurotransmitter that acts on purinergic receptors. In spite of the presence of purinergic receptors in forebrain areas involved with fluid-electrolyte balance, the effect ...
D.R.G. de Faria+3 more
doaj
VPAC Receptor Subtypes Tune Purinergic Neuron-to-Glia Communication in the Murine Submucosal Plexus
The enteric nervous system (ENS) situated within the gastrointestinal tract comprises an intricate network of neurons and glia which together regulate intestinal function. The exact neuro-glial circuitry and the signaling molecules involved are yet to be
Pieter Vanden Berghe+6 more
doaj +1 more source
ATP as a presynaptic modulator [PDF]
© 2000 Elsevier Science Inc.There is considerable evidence that ATP acts as a fast transmitter or co-transmitter in autonomic and sensory nerves mostly through activation of ionotropic P2X receptors but also through metabotropic P2Y receptors. By analogy,
Cunha, Rodrigo A., Ribeiro, J. A.
core +1 more source
Background The translocation of neuronal nitric oxide synthase (nNOS) from the cytosol to the membrane is functionally coupled to the activation of N-methyl-D-aspartate (NMDA) receptors at synapses.
Ohnishi Takayuki+2 more
doaj +1 more source