Results 131 to 140 of about 5,154 (256)

Extracellular ATP activates NFAT-dependent gene expression in neuronal PC12 cells via P2X receptors

open access: yesBMC Neuroscience, 2011
Background Treatment of neuronal PC12 cells with ATP induces depolarisation and increases intracellular calcium levels via purinergic receptors. In many cell types, sustained elevation of intracellular calcium levels cause changes in gene expression via ...
Becker Walter   +2 more
doaj   +1 more source

Emerging factors affecting peri‐implant bone metabolism

open access: yesPeriodontology 2000, Volume 94, Issue 1, Page 27-78, February 2024.
Abstract Implant dentistry has evolved to the point that standard implant osseointegration is predictable. This is attributed in part to the advancements in material sciences that have led toward improvements in implant surface technology and characteristics.
Angel Insua   +4 more
wiley   +1 more source

Abordagens frequentista e bayesiana para avaliação genética de bovinos da raça Canchim para características de crescimento. [PDF]

open access: yes, 2011
Este trabalho foi realizado com os objetivos de: a) comparar os componentes de (co)variância obtidos por meio dos métodos da Máxima Verossimilhança Restrita (REML) e da inferência bayesiana (IB); b) realizar a avaliação genética do peso à desmama (P240 ...
ALENCAR, M. M. de   +2 more
core  

P2Y11 receptors : properties, distribution and functions [PDF]

open access: yes, 2017
The P2Y11 receptor is a G protein-coupled receptor that is stimulated by endogenous purine nucleotides, particularly ATP. Amongst P2Y receptors it has several unique properties; 1) it is the only human P2Y receptor gene that contains an intron in the ...
Kennedy, Charles
core   +1 more source

Skeletal Class III phenotype: Link between animal models and human genetics: A scoping review

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 342, Issue 1, Page 21-44, January 2024.
Genetic variants associated with skeletal Class III malocclusion identified in animal models. Identified variants emphasize the role of BMP and TGF‐β signaling in bone growth and ossification regulation. Abstract This study aimed to identify evidence from animal studies examining genetic variants underlying maxillomandibular discrepancies resulting in ...
Alexandra Dehesa‐Santos   +2 more
wiley   +1 more source

P2X4 receptor function in the nervous system and current breakthroughs in pharmacology [PDF]

open access: yes, 2017
ATP is a well-known extracellular signalling molecule and neurotransmitter known to activate purinergic P2X receptors. Information has been elucidated about the structure and gating of P2X channels following the determination of the crystal structure of ...
Abdelrahman   +174 more
core   +2 more sources

Antidipsogenic effects of central adenosine-5'-triphosphate

open access: yesBrazilian Journal of Medical and Biological Research, 2009
Besides other physiological functions, adenosine-5'-triphosphate (ATP) is also a neurotransmitter that acts on purinergic receptors. In spite of the presence of purinergic receptors in forebrain areas involved with fluid-electrolyte balance, the effect ...
D.R.G. de Faria   +3 more
doaj  

VPAC Receptor Subtypes Tune Purinergic Neuron-to-Glia Communication in the Murine Submucosal Plexus

open access: yesFrontiers in Cellular Neuroscience, 2017
The enteric nervous system (ENS) situated within the gastrointestinal tract comprises an intricate network of neurons and glia which together regulate intestinal function. The exact neuro-glial circuitry and the signaling molecules involved are yet to be
Pieter Vanden Berghe   +6 more
doaj   +1 more source

ATP as a presynaptic modulator [PDF]

open access: yes, 2000
© 2000 Elsevier Science Inc.There is considerable evidence that ATP acts as a fast transmitter or co-transmitter in autonomic and sensory nerves mostly through activation of ionotropic P2X receptors but also through metabotropic P2Y receptors. By analogy,
Cunha, Rodrigo A., Ribeiro, J. A.
core   +1 more source

Translocation of neuronal nitric oxide synthase to the plasma membrane by ATP is mediated by P2X and P2Y receptors

open access: yesMolecular Pain, 2009
Background The translocation of neuronal nitric oxide synthase (nNOS) from the cytosol to the membrane is functionally coupled to the activation of N-methyl-D-aspartate (NMDA) receptors at synapses.
Ohnishi Takayuki   +2 more
doaj   +1 more source

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