Results 141 to 150 of about 5,261 (261)

Mechanisms of constitutive and ATP-evoked ATP release in neonatal mouse olfactory epithelium

BMC Neuroscience, 2012
Background ATP is an extracellular signaling molecule with many ascribed functions in sensory systems, including the olfactory epithelium. The mechanism(s) by which ATP is released in the olfactory epithelium has not been investigated.
Hayoz Sébastien, Jia Cuihong, Hegg CC
doaj   +1 more source

Emerging key roles for P2X receptors in the kidney [PDF]

, 2013
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides. Whilst there is a wealth of literature
Birch, R. E., Peppiatt-Wildman, Claire M., Schwiebert, E. M., Wildman, Scott S.P.   +3 more
core   +2 more sources

Fast Ca2+ Transients of Inner Hair Cells Arise Coupled and Uncoupled to Ca2+ Waves of Inner Supporting Cells in the Developing Mouse Cochlea

Frontiers in Molecular Neuroscience, 2018
Before the onset of hearing, which occurs around postnatal day 12 (P12) in mice, inner hair cells (IHCs) of the immature cochlea generate sound-independent Ca2+ action potentials (APs), which stimulate the auditory pathway and guide maturation of ...
Tobias Eckrich, Kerstin Blum, Ivan Milenkovic, Jutta Engel   +3 more
doaj   +1 more source

Cell cycle regulation of astrocytes by extracellular nucleotides and fibroblast growth factor-2 [PDF]

, 2005
Extracellular ATP enhances the mitogenic activity of fibroblast growth factor-2 (FGF2) in astrocytes, but the molecular mechanism underlying this synergistic interaction is not known.
BF King, C Ho, CJ Gallagher, CJ Marshall, CJ Sherr, D Ferrari, D Schiffer, D Wang, F Doetsch, F Eclancher, F Perraud, FP Gendron, FP Gendron, G Burnstock, G Lenz, G Lenz, GL Peterson, H Franke, J Silver, JB Cavanagh, JD Weber, JJ Yang, JL Ridet, Joseph T. Neary, JT Neary, JT Neary, JT Neary, JT Neary, JT Neary, K Roovers, M Fumagalli, MC Jacques-Silva, MP Abbracchio, MP Rathbone, N Huang, N Latov, NE Olson, OR Baricordi, P Zanovello, Q Zhu, QB She, R Seger, RM Tombes, RS Ostrom, SJ Hill-Felberg, SP Finklestein, UK Laemmli, V Budagian, W Panenka, WT Norton, Y Nakatsuji, Y Takamiya, YJ Hou, You-Fang Shi, Yuan Kang   +54 more
core   +2 more sources

The Ionotropic P2X4 Receptor has Unique Properties in the Heart by Mediating the Negative Chronotropic Effect of ATP While Increasing the Ventricular Inotropy

Frontiers in Pharmacology, 2019
Background: Mounting evidence indicate that reducing the sinoatrial node (SAN) activity may be a useful therapeutic strategy to control of heart failure.
Bruno Bragança, Bruno Bragança, Sílvia Nogueira-Marques, Fátima Ferreirinha, Ana Patrícia Fontes-Sousa, Paulo Correia-de-Sá   +5 more
doaj   +1 more source

Experimental inhibition of proliferative retinopathy [PDF]

, 2012
Retinal ischemic diseases like retinopathy of prematurity (ROP), diabetic retinopathy (DRP) and retinal vein occlusion, with preretinal neovascularization (angiogenesis) that may lead to vitreous hemorrhages and retinal detachment with subsequent vision ...
Almlöf Sarman, Sylvia
core   +1 more source

Pure-Circuit: Tight Inapproximability for PPAD [PDF]

, 2022
Argyrios Deligkas, John Fearnley, Alexandros Hollender, Themistoklis Melissourgos   +3 more
openalex   +1 more source

Salt-Sensitive Signaling Networks in the Mediation of K+/Na+ Homeostasis Gene Expression in Glycyrrhiza uralensis Roots

Frontiers in Plant Science, 2017
We investigated the effects of salt-sensitive signaling molecules on ionic fluxes and gene expression related to K+/Na+ homeostasis in a perennial herb, Glycyrrhiza uralensis, during short-term NaCl stress (100 mM, 24 h).
Tao Lang, Shurong Deng, Shurong Deng, Nan Zhao, Chen Deng, Yinan Zhang, Yanli Zhang, Huilong Zhang, Gang Sa, Jun Yao, Caiwu Wu, Yanhong Wu, Qun Deng, Shanzhi Lin, Jianxin Xia, Shaoliang Chen   +15 more
doaj   +1 more source

The Rainbow at the End of the Line --- A PPAD Formulation of the Colorful Carathéodory Theorem with Applications [PDF]

, 2016
Frédéric Meunier, Wolfgang Mulzer, Pauline Sarrabezolles, Yannik Stein   +3 more
openalex   +1 more source

Selective stimulation of catecholamine release from bovine adrenal chromaffin cells by an ionotropic purinergic receptor sensitive to 2-methylthio ATP

BMC Neuroscience, 2007
Background 2-Methylthioadenosine 5'-triphosphate (2-MeSATP), formerly regarded as a specific P2Y (metabotropic) purinergic receptor agonist, stimulates Ca2+ influx and evokes catecholamine release from adrenal chromaffin cells.
Castro Enrique, Tomé Ângelo R, Santos Rosa M, Rosário Luís M   +3 more
doaj   +1 more source