Activity Analysis of the P2X Receptor Antagonist PPADS against Signal Transducer and Activator of Transcription Proteins. [PDF]
ChembiochemThe P2X receptor antagonist PPADS possesses activity against members of the signal transducer and activator of transcription (STAT) family of transcription factors, in particular STAT4, STAT5a, and STAT5b. PPADS protects STAT4 and STAT5a/STAT5b from thermal degradation in cell lysates to a higher extent than STAT3.
Berg A, Gräber M, Berg T.
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Selective antagonism by PPADS at P2X‐purinoceptors in rabbit isolated blood vessels [PDF]
British Journal of Pharmacology, 1994 1. Pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid (PPADS), a P2-purinoceptor antagonist, was investigated for its ability to antagonize: (1) P2X-purinoceptor-mediated contractions of the rabbit central ear artery and saphenous artery evoked by either alpha,beta-methylene ATP (alpha,beta-MeATP) or electrical field stimulation (EFS); (2) P2Y ...
A. Ziganshin +5 more
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The Hairy Ball problem is PPAD-complete [PDF]
Journal of Computer and System Sciences, 2021 The Hairy Ball Theorem states that every continuous tangent vector field on an even-dimensional sphere must have a zero. We prove that the associated computational problem of (a) computing an approximate zero is PPAD-complete, and (b) computing an exact zero is FIXP-hard.
Paul W. Goldberg, Alexandros Hollender
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Inhibitory action of PPADS on relaxant responses to adenine nucleotides or electrical field stimulation in guinea‐pig taenia coli and rat duodenum [PDF]
British Journal of Pharmacology, 1995 U. Windscheif +7 more
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Investigation of the actions of PPADS, a novel P2X‐purinoceptor antagonist, in the guinea‐pig isolated vas deferens [PDF]
British Journal of Pharmacology, 1994 G. J. McLaren +5 more
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, 2008 Scarf's lemma is one of the fundamental results in combinatorics, originally introduced to study the core of an N-person game. Over the last four decades, the usefulness of Scarf's lemma has been demonstrated in several important combinatorial problems seeking "stable" solutions.
Shiva Kintali
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PPADS: an antagonist at endothelial P2Y‐purinoceptors but not P2U‐purinoceptors [PDF]
British Journal of Pharmacology, 1995 C. Brown, Bhavna Tanna, M. Boarder
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P2 receptor antagonist PPADS inhibits mesangial cell proliferation in experimental mesangial proliferative glomerulonephritis. [PDF]
Kidney International, 2002 Sylvia Rost +5 more
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PPADS selectively antagonizes P2X‐purinoceptor‐mediated responses in the rabbit urinary bladder [PDF]
British Journal of Pharmacology, 1993 A. Ziganshin +6 more
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