Porphyromonas gulae and PPAD antibodies are not related to citrullination in rheumatoid arthritis [PDF]
Clinical Oral Investigations, 2023 Abstract Introduction Porphyromonas gulae have the enzyme PPAD, as P. gingivalis, which is responsible for citrullination related to the pathophysiology of rheumatoid arthritis and periodontitis; this implies the presence of two species of PPAD-producing bacteria in the mouth as well as the presence of citrullinated ...
Camilo Castellar‐Mendoza +4 more
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PULMONARY VASCULAR RESISTANCE AND Ppad-PlaGRADIENTS [PDF]
Anesthesiology, 1980 E. D. Canada, Jonathan L. Benumof
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PEEP INDUCED Ppad-PlaGRADIENT [PDF]
Anesthesiology, 1979 E. A. Meathe +4 more
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Expression of purinergic receptors on microglia in the animal model of choroidal neovascularisation
Scientific Reports, 2021 To investigate the effect of P2 receptor on microglia and its inhibitor PPADS on choroidal neovascularization. Forty CX3CR1GFP/+ mice were randomly divided into 8 groups. In addition to the normal group, the rest of groups were receiving laser treatment.
Lu Li +5 more
doaj +1 more source
Candidalysin Is the Hemolytic Factor of Candida albicans
Toxins, 2022 Candida albicans produces an important virulence factor, the hypha-associated Ece1-derived secreted peptide toxin candidalysin, which is crucial for the establishment of mucosal and systemic infections. C.
Selene Mogavero +11 more
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Biaryl Phosphate-Based Inhibitors of the Transcription Factor STAT4. [PDF]
ChemMedChemThe transcription factor signal transducer and activator of transcription (STAT)4 is a potential target for autoimmune diseases. p‐Biphenyl phosphate is reported as an inhibitor of the STAT4 Src homology 2 domain and it is developed to the phosphonate Stafori‐1.
Brovchenko N +3 more
europepmc +2 more sources
Pure-Circuit: Strong Inapproximability for PPAD
2022 IEEE 63rd Annual Symposium on Foundations of Computer Science (FOCS), 2022 The current state-of-the-art methods for showing inapproximability in PPAD arise from the ε-Generalized-Circuit (ε-GCircuit) problem. Rubinstein (2018) showed that there exists a small unknown constant ε for which ε-GCircuit is PPAD-hard, and subsequent work has shown hardness results for other problems in PPAD by using ε-GCircuit as an intermediate ...
Deligkas, A +3 more
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Defining the role of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) in rheumatoid arthritis through the study of PPAD biology [PDF]
Annals of the Rheumatic Diseases, 2014 Antibodies to citrullinated proteins are a hallmark of rheumatoid arthritis (RA). Porphyromonas gingivalis peptidylarginine deiminase (PPAD) has been implicated in the initiation of RA by generating citrullinated neoantigens and due to its ability to autocitrullinate.To define the citrullination status and biology of PPAD in P gingivalis and to ...
Maximilian F. Konig +4 more
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Co‐existence of P2Y‐ and PPADS‐insensitive P2U‐purinoceptors in endothelial cells from adrenal medulla [PDF]
British Journal of Pharmacology, 1996 Jesús Mateo +2 more
semanticscholar +2 more sources
Delegation with Updatable Unambiguous Proofs and PPAD-Hardness [PDF]
, 2020 In this work, we construct an updatable and unambiguous delegation scheme based on the decisional assumption on bilinear groups introduced by Kalai, Paneth and Yang [STOC 2019]. Using this delegation scheme, we show PPAD-hardness (and hence the hardness of computing Nash equilibria) based on the quasi-polynomial hardness of this bilinear group ...
Yael Tauman Kalai +2 more
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