Results 51 to 60 of about 5,154 (256)

Release of ATP in the ventral medulla during hypoxia in rats: role in hypoxic ventilatory response [PDF]

, 2005
P2X2 receptor subunits of the ATP-gated ion channels are expressed by physiologically identified respiratory neurons in the ventral respiratory column, implicating ATP in the control of respiratory activity.
Dale, Nicholas, Gourine, Alexander V., Llaudet, Enrique, Spyer, K. Michael   +3 more
core   +2 more sources

ATP mediates NADPH oxidase/ROS generation and COX-2/PGE2 expression in A549 cells: role of P2 receptor-dependent STAT3 activation. [PDF]

PLoS ONE, 2013
BACKGROUND: Up-regulation of cyclooxygenase (COX)-2 and its metabolite prostaglandin E(2) (PGE(2)) are frequently implicated in lung inflammation. Extracellular nucleotides, such as ATP have been shown to act via activation of P2 purinoceptors, leading ...
Shin-Ei Cheng, I-Ta Lee, Chih-Chung Lin, Wan-Ling Wu, Li-Der Hsiao, Chuen-Mao Yang   +5 more
doaj   +1 more source

Possible neuroprotective role of P2X2 in the retina of diabetic rats

Diabetology & Metabolic Syndrome, 2018
Background Purinergic receptors are expressed in different tissues including the retina. These receptors are involved in processes like cell growth, proliferation, activation and survival. ATP is the major activator of P2 receptors. In diabetes, there is
Jorge E. Mancini, Gustavo Ortiz, Constanza Potilinstki, Juan P. Salica, Emiliano S. Lopez, J. Oscar Croxatto, Juan E. Gallo   +6 more
doaj   +1 more source

Synthesis and Structure-Activity Relationships of Pyridoxal-6-arylazo-5'-phosphate and Phosphonate Derivatives as P2 Receptor Antagonists. [PDF]

, 1998
Novel analogs of the P2 receptor antagonist pyridoxal-5'-phosphate-6-phenylazo-2',4'-disulfonate (PPADS) were synthesized. Modifications were made through functional group substitution on the sulfophenyl ring and at the phosphate moiety through the ...
Boyer, José L., Burnstock, Geoffrey, Camaioni, Emidio, Harden, T. Kendall, Jacobson, Kenneth A., Ji, Xiao-Duo, Kim, Heaok, Kim, Yong-Chul, King, Brian F., Mohanram, Arvind, Rychkov, Alexei, Wildman, Scott S.P., Yoburn, Joshua, Ziganshin, Airat U.   +13 more
core   +3 more sources

ATP signaling in the integrative neural center of Aplysia californica

Scientific Reports, 2021
ATP and its ionotropic P2X receptors are components of the most ancient signaling system. However, little is known about the distribution and function of purinergic transmission in invertebrates.
János Györi, Andrea B. Kohn, Daria Y. Romanova, Leonid L. Moroz   +3 more
doaj   +1 more source

PPAD: Privacy Preserving Group-Based ADvertising in Online Social Networks

2018 IFIP Networking Conference (IFIP Networking) and Workshops, 2018
Services provided as free by Online Social Networks (OSN) come with privacy concerns. Users’ information kept by OSN providers are vulnerable to the risk of being sold to the advertising firms. To protect user privacy, existing proposals utilize data encryption, which prevents the providers from monetizing users’ information.
Sanaz Taheri Boshrooyeh, Alptekın Küpçü, Öznur Özkasap   +2 more
openalex   +5 more sources

PPAD-complete approximate pure Nash equilibria in Lipschitz games

Theoretical Computer Science, 2023
Lipschitz games, in which there is a limit λ (the Lipschitz value of the game) on how much a player's payoffs may change when some other player deviates, were introduced about 10 years ago by Azrieli and Shmaya. They showed via the probabilistic method that n-player Lipschitz games with m strategies per player have ϵ-approximate pure Nash equilibria ...
Goldberg, P, Katzman, M
openaire   +2 more sources

P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]

, 2008
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
Brian F. King, Bucheimer RE, Dai LJ, Dubyak GR, Egan TM, Inscho EW, King BF, Lazarowski ER, Lazarowski ER, Lehrmann H, Leipziger J, Li L, McCoy DE, North RA, Pelegrin P, Piper AS, Ralevic V, Schwiebert EM, Scott S.P. Wildman, Shirley DG, Taylor AL, Unwin RJ, Vekaria R, Wildman SS, Wildman SS, Wildman SS, Wildman SS, Wildman SS, Wolff SC, Zhang Y   +29 more
core   +1 more source

The effect of PPADS as an antagonist of inositol (1,4,5)trisphosphate induced intracellular calcium mobilization [PDF]

British Journal of Pharmacology, 1996
Brain capillary endothelial cells responded to uridine 5′‐triphosphate (UTP) and adenosine 5′‐triphosphate (ATP) by activation of phospholipase C and by large changes in [Ca2+]i. These cells expressed mRNA sequences identical to the sequence of the P2Y2‐purinoceptor of rat pituitaries.Pyridoxalphosphate‐6‐azophenyl‐2′,4′‐disulphonic acid (PPADS) at 100
P. Vigne, P. Pacaud, V. Urbach, E. Feolde, J. Breittmayer, C. Frelin   +5 more
semanticscholar   +4 more sources

Multiple P2Y receptors couple to calcium-dependent, chloride channels in smooth muscle cells of the rat pulmonary artery

Respiratory Research, 2005
Background Uridine 5'-triphosphate (UTP) and uridine 5'-diphosphate (UDP) act via P2Y receptors to evoke contraction of rat pulmonary arteries, whilst adenosine 5'-triphosphate (ATP) acts via P2X and P2Y receptors.
Gurney Alison M, Chootip Krongkarn, Kennedy Charles   +2 more
doaj   +1 more source