Results 281 to 290 of about 121,549 (307)

Mertk promotes early microglial-mediated synaptic engulfment in Alzheimer's disease. [PDF]

Theranostics
Wu Y, Fan Y, Bao S, Song Y, Wang R, Wu J, Liu X, Jin J, Kong L, Hou B, Liang P, Chen T, Liu W, Peng B, He F, Zhou Y, Xu J, Chen Y, Han S, Yin J, He X.   +20 more
europepmc   +1 more source

Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid, Muhammad Tauseef Sultan, Muhammad Maaz, Shehnshah Zafar, Anum Shoukat, Nudrat Khursheed, Matteo Bordiga, Amna Junaid   +7 more
wiley   +1 more source

The controversial role of linoleic acid in cardiometabolic health: from molecular pathways to human studies. [PDF]

Front Nutr
Berkowitz L, Araneda P, Cofré G, Sara D, Olsen M, Urzúa I, Pérez D, Rigotti A.   +7 more
europepmc   +1 more source

Ginsenoside Rg1 as a Multifunctional Therapeutic Agent: Pharmacological Properties, Molecular Mechanisms and Clinical Perspectives in Complementary Medicine

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés, Enrique Lima, Lorena Duarte‐Peña, Sheila I. Peña‐Corona, Zainab M. Almarhoon, Rajesh Kaverikana, Shivaprasad Shetty Mangalpady, Vinayaka Babu Shet, Nikshitha Manjeshwar, Javad Sharifi‐Rad, Jen‐Tsung Chen, Gerardo Leyva‐Gómez, William N. Setzer, Daniela Calina   +13 more
wiley   +1 more source

PPARγ-Axl axis ameliorates intervertebral disc degeneration by activating PI3K/AKT-mediated autophagy to suppress ferroptosis. [PDF]

Cell Mol Biol Lett
Sun G, Xu D, Jiang Y, Su K, Lu J, Zhou C.   +5 more
europepmc   +1 more source

Molecular Mechanism of Dihydroquercetin in Ameliorating Metabolic Dysfunction–Associated Steatotic Liver Disease: Insights Into the HIF‐1α/VEGF Pathway

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Dihydroquercetin (DHQ) alleviates lipid metabolic dysfunction and hepatic inflammation in MASLD. Mechanistically, DHQ modulates the HIF‐1α/VEGF signaling pathway, contributing to improved liver homeostasis. ABSTRACT Dihydroquercetin (DHQ) is a plant‐derived flavonoid with well‐documented antioxidant and anti‐inflammatory properties. This study aimed to
Xinyue Zhang, Han Zhang, Bing Wu, Pengfei Wu, Ao Shen, Cheng Zhang, Yuqiao Zeng, Yanjun Wang, Hao Xu, Yiyu He, Likun Wang   +10 more
wiley   +1 more source

Pivotal contribution of super-enhancer-driven KLF6 expression to the adipogenesis of human adipose-derived stem cells. [PDF]

Inflamm Regen
Nguyen MP, Yamagata K, Nguyen AP, Zhang T, Sakai H, Ngo UT, Shan Y, Otsuka T, Huong NTD, Aritomi T, Yuan M, Kato S, Tanaka Y, Nakayamada S.   +13 more
europepmc   +1 more source

The ZNF148‐ZEB1‐AS1‐IGF2BP2‐NOD2 Axis Drives Microglial Antipneumococcal Immunity in Bacterial Meningitis

Glia, Volume 74, Issue 2, February 2026.
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Xiufu Hu, Fang Jiang, Xinjie Liu, Ling Li, Ruimei Hu, Meng Dong, Aihua Cao   +6 more
wiley   +1 more source

Reversing Alcohol-Dependent Effects on HIV Replication: Are There Roles for Pioglitazone and N-acetylcysteine? [PDF]

Am J Respir Cell Mol Biol
Manicone AM, Brune JE.
europepmc   +1 more source

MiR‐18a‐5p Attenuates Oxidative Stress and Inhibits Lipid Accumulation in Alcoholic Fatty Liver by Activating the CYP1A1‐PPAR Axis

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Lipid deposition in alcoholic fatty liver disease (AFL) represents an early stage in alcoholic liver disease progression and may contribute to carcinogenesis. MicroRNAs (miRNAs) play critical regulatory roles in liver biological processes. Methods In this study, we explored the miR‐18a‐5p/CYP1A1/PPAR axis in AFL using bioinformatics
XueMei Zhang, Wei Li, Ubaid Ullah, Ning Li, XinYu Geng, JiHan Qi, HongLiang Chen, Xu Zhang, Ying Hu, Lingling Yang, ShiZhu Jin   +10 more
wiley   +1 more source