Results 291 to 300 of about 121,549 (307)

Saffron as a natural modulator of reverse cholesterol transport genes in atherosclerotic rabbits, with molecular docking insights. [PDF]

open access: yesSci Rep
Mohd Zainal Abidin Shukri Y   +8 more
europepmc   +1 more source

<i>PLIN5</i> Promotes Lipid Reconstitution in Goat Intramuscular Fat via the PPARγ Signaling Pathway. [PDF]

open access: yesBiology (Basel)
Dai Y   +10 more
europepmc   +1 more source

USP2-mediated PPARγ stabilization promotes hepatocellular carcinoma progression and M2 macrophage polarization via oleic acid. [PDF]

open access: yesJ Immunother Cancer
Cao J   +10 more
europepmc   +1 more source

Developing QSAR Models with Defined Applicability Domains on PPARγ Binding Affinity Using Large Data Sets and Machine Learning Algorithms.

Environmental Science and Technology, 2021
Chemicals may cause adverse effects on human health through binding to peroxisome proliferator-activated receptor γ (PPARγ). Hence, binding affinity is useful for evaluating chemicals with potential endocrine-disrupting effects.
Zhongyu Wang, Jingwen Chen, H. Hong
semanticscholar   +1 more source

Comparative Design, In Silico Dockingand Predictive ADME/ TOX Properties of Some Novel 2, 4-hydroxy Derivatives of Thiazolidine-2, 4-diones as PPARγ Modulator

Journal of Pharmaceutical Chemistry, 2017
Peroxisome proliferated receptors (PPARs) are important targets for drugs used in the treatment of various metabolic disorders. We have reported 4-hydroxy benzylidene derivatives of thiazolidine-2,4-diones with reversed orientation in the active site of PPARγin our earlier communication.
Sabina Yasmin   +4 more
openaire   +1 more source

PPARγ preservation via promoter demethylation alleviates osteoarthritis in mice

Annals of the Rheumatic Diseases, 2019
Objectives Osteoarthritis (OA) is the most common degenerative joint disease in aged population and its development is significantly influenced by aberrant epigenetic modifications of numerous OA susceptible genes; however, the precise mechanisms that ...
Xiaobo Zhu   +5 more
semanticscholar   +1 more source

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