Results 301 to 307 of about 121,549 (307)

Curcumin inhibits cigarette smoke-induced inflammation via modulating the PPARγ-NF-κB signaling pathway.

Food & Function, 2019
Peroxisome proliferator-activated receptor gamma (PPARγ), a ligand-activated nuclear hormone receptor, is considered to be a potential target for the anti-inflammatory treatment of COPD, and its anti-inflammatory efficacy is likely related to the ...
Qiuping Li, Jing Sun, N. Mohammadtursun, Jinfeng Wu, Jingcheng Dong, Lulu Li   +5 more
semanticscholar   +1 more source

PPARγ is a gatekeeper for extracellular matrix and vascular cell homeostasis: beneficial role in pulmonary hypertension and renal/cardiac/pulmonary fibrosis.

Current opinion in nephrology and hypertension, 2019
PURPOSE OF REVIEW Pulmonary arterial hypertension (PAH) is characterized by pulmonary arterial endothelial cell (PAEC) dysfunction and apoptosis, pulmonary arterial smooth muscle cell (PASMC) proliferation, inflammation, vasoconstriction, and metabolic ...
G. Kökény, L. Calvier, E. Legchenko, P. Chouvarine, M. Mózes, G. Hansmann   +5 more
semanticscholar   +1 more source

PPARγ and Diabetes: Beyond the Genome and Towards Personalized Medicine

Current Diabetes Reports, 2021
Simona Cataldi, Valerio Costa, A. Ciccodicola, Marianna Aprile   +3 more
semanticscholar   +1 more source

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ) (*)

Journal of Biological Chemistry, 1995
J. Lehmann, L. Moore, T. Smith-Oliver, W. Wilkison, T. Willson, S. Kliewer   +5 more
semanticscholar   +1 more source

Melatonin suppresses platelet activation and function against cardiac ischemia/reperfusion injury via PPARγ/FUNDC1/mitophagy pathways

Journal of Pineal Research, 2017
Hao Zhou, Dandan Li, Pingjun Zhu, Shunying Hu, N. Hu, Sai Ma, Y. Zhang, Tianwen Han, Jun Ren, F. Cao, Yundai Chen   +10 more
semanticscholar   +1 more source

Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension

Nature, 1999
I. Barroso, M. Gurnell, V. Crowley, M. Agostini, J. Schwabe, M. Soos, G. Maslen, T. Williams, H. Lewis, A. J. Schafer, V. Chatterjee, S. O’Rahilly   +11 more
semanticscholar   +1 more source