Results 71 to 80 of about 430,860 (160)
Biotechnology & Biotechnological Equipment, 2019 This study aimed to investigate the effect of upregulated peroxisome proliferator-activated receptor-gamma (PPAR-γ) activity on cyclooxygenase 2 (COX-2) expression and N-methyl-d-aspartic acid (NMDA)-induced excitatory neurotoxicity in primary cultured ...
Qi-Fang Weng +7 more
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Acta Biochimica IndonesianaBackground: Diabetes mellitus remains one of the most dangerous illnesses worldwide. The PPAR-gamma protein plays a crucial role in lipid and carbohydrate metabolism, making it a key target for diabetes therapy.
Anjar Hermadi Saputro +3 more
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Activated AMPK inhibits PPAR-α and PPAR-γ transcriptional activity in hepatoma cells
, 2011 AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor-α (PPAR-α) are critical regulators of short-term and long-term fatty acid oxidation, respectively. We examined whether the activities of these molecules were coordinately
Suthat Liangpunsakul +4 more
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Role of Peroxisome Proliferator-Activated Receptor γ in Ocular Diseases
Journal of Ophthalmology, 2015 Peroxisome proliferator-activated receptor γ (PPAR γ), a member of the nuclear receptor superfamily, is a ligand-activated transcription factor that plays an important role in the control of a variety of physiological processes.
Su Zhang, Hongwei Gu, Nan Hu
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Zhongguo shiyan zhenduanxue, 2008 目的观察过氧化物酶体增殖激活物受体（PPAR-γ）在结直肠癌中的表达,探讨其意义。方法采用免疫组织化学方法检测38例结直肠癌及20例癌旁相对正常结直肠组织中PPAR-γ蛋白的表达,并进一步分析PPAR-γ蛋白在不同结直肠癌病理组织类型中的表达。结果PPAR-γ在结直肠癌中表达阳性率为63.16%（24/38）,在相对正常结直肠组织中表达阳性率为30.00%（6/20）,PPAR-γ在结直肠癌中表达阳性率明显高于癌旁相对正常结直肠组织 ...
舒振波, 操海萍, 盖宝东, 王巍
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Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion
, 2017 Perturbation of the gut-associated microbial community may underlie many human illnesses, but the mechanisms that maintain homeostasis are poorly understood.
Giulivi, Cecilia +37 more
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, 2009 Peroxisome proliferator-activated receptor-γ (PPAR-γ) has already been considered as an attractive molecular target for the treatment of human metabolic disorders.
Giaginis, C. +2 more
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PPAR-γ deficient macrophages exhibited pro-inflammatory and pro-fibrotic gene expression.
, 2019 WT (Ppargfl/fl) or PPAR-γ cKO (PpargΔLyz2) mice were infected with influenza. Mice were sacrificed for macrophage isolation at 30 d.p.i. (A) Lung cells were stained with anti-CD45, anti-Ly6G, anti-MerTK and anti-CD64.
Eva M. Carmona (7465466) +13 more
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, 2012 Representative photomicrographs of colons from PPAR γ-expressing (PPAR γ flfl Cre−, top panels A–C) and macrophage-specific PPAR γ null (PPAR γ flfl Cre+, bottom panels D–F) control untreated (A&D), CLA-treated (B&E), and VSL#3-treated (C&F) mice.
Mireia Pedragosa (120080) +11 more
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Behavioural Neurology, 2018 Background and Purpose. PPAR-γ is a transcriptional factor which is associated with promoting hematoma clearance and reducing neurological dysfunction after intracerebral hemorrhage (ICH). Haptoglobin- (Hp-) hemoglobin- (Hb-) CD163 acts as a main pathway
Gaiqing Wang +5 more
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