Results 201 to 210 of about 76,534 (232)
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PPAR-gamma in Cushing's disease.

Pituitary, 2006
The majority of pituitary tumors that cause Cushing's disease are small (
openaire   +1 more source

Functions of PPAR Gamma in Macrophages and Atherosclerosis

2002
The peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily whose activity can be modulated by polyunsaturated fatty acids, prostaglandins, eicosanoids, and various synthetic ligands [1]. There are three PPARs, termed α, δ and λ [2].
Ajay Chawla   +4 more
openaire   +1 more source

PPAR-gamma agonists: Potential modulators of autophagy in obesity

European Journal of Pharmacology, 2021
Amir Hossein Faghfouri   +2 more
exaly  

Klotho is a target gene of PPAR-gamma.

Kidney international, 2009
Klotho is an anti-aging gene whose expression is regulated by many stimuli. Here we examined the transcriptional regulation of the klotho gene by peroxisome proliferator-activated receptor-gamma (PPAR-gamma). The PPAR-gamma agonists thiazolidinediones increased both klotho mRNA and protein expression in HEK293 cells and several renal epithelial cell ...
Hong, Zhang   +7 more
openaire   +1 more source

PPAR gamma and the treatment of insulin resistance.

Trends in endocrinology and metabolism: TEM, 2001
Numerous studies across several population groups have indicated that insulin resistance plays a central role in the development of type 2 diabetes mellitus (T2DM). Moreover, this disorder is also strongly associated with other metabolic syndromes, including hypertension, dyslipidemias and polycystic ovarian syndrome (PCOS).
J M, Olefsky, A R, Saltiel
openaire   +1 more source

Role of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Different Disease States: Recent Updates

Current Medicinal Chemistry, 2021
Suvadeep Mal   +2 more
exaly  

[PPAR gamma--the master of thrifty genes].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2004
Peroxisome proliferation is a cellular response to many chemical compounds affects including natural and modified fatty acids, phthalate and adipate ester plasticizers, leukotriene antagonists, acetylsalicylic acid and certain pathophysiological conditions including dramatic change of cellular morphology and enzymatic activity. Peroxisome proliferation
Yong-sheng, Chang, Fu-de, Fang
openaire   +1 more source

Phosphorylation of PPAR-gamma in ALS

2012
Objective: Oxidative stress, mitochondrial dysfunction and neuroin-flammation are pathological processes involved in amyotrophic lateralsclerosis (ALS), a neurodegenerative disorder characterized by a lossof upper and lower motor neurons. In animal models of neuro-degeneration several experiments using Thiazolidinediones (TZD),synthetic PPARγagonists ...
openaire   +1 more source

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