Bisphenol a and polycystic ovary syndrome in reproductive-age women: mechanistic exploration via network toxicology and molecular docking. [PDF]
Peng C, Wang C, Chen J, Chen H.
europepmc +1 more source
ASXL1 impairs osteoclast formation by epigenetic regulation of NFATc1 [PDF]
Abu-Amer, Yousef +6 more
core +1 more source
Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise +5 more
wiley +1 more source
Peroxisome proliferation–activated receptor-γ (PPARG; PPARγ) [PDF]
openaire +3 more sources
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen +11 more
wiley +1 more source
Systems-Level Transcriptomic Integration Reveals a Core Metaflammatory Network Linking Type 2 Diabetes and HBV Infection to Cholangiocarcinoma Progression. [PDF]
Md Rasadul H +11 more
europepmc +1 more source
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu +7 more
wiley +1 more source
System biology and network-based approach to identify the therapeutic signatures and potential inhibitors against polycystic lipomembranous osteodysplasia with Sclerosing Leukoencephalopathy. [PDF]
Bokhari BT +7 more
europepmc +1 more source
Transient SUMOylation inhibition in human pre-adipocytes stably imprints a transcriptional beiging fate. [PDF]
Nothnagel PMC +10 more
europepmc +1 more source
Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu +3 more
wiley +1 more source

