Results 31 to 40 of about 38,455 (298)

Development of metabolic syndrome at a young age as a manifestation of familial partial lipodystrophy type 3 (PPARG mutation): the first description of its clinical case in Russia

Сахарный диабет, 2015
Metabolic syndrome (MS) is extremely common (20%–25% of the world’s population), and its diagnostic criteria are defined and well known. It has been shown that patients who have MS are twice as likely to die from a cardiovascular complication and three ...
Ekaterina Leonidovna Sorkina, Marina Fedorovna Kalashnikova, Natalya Vyacheslavovna Likhodey, Ekaterina Olegova Koksharova, Dmitry Vladimirovich Ustyuzhanin, Alexander Yuryevich Mayorov, Marina Vladimirovna Shestakova, Anatoly Nikolaevich Tiulpakov   +7 more
doaj   +1 more source

A Synergistic Antiobesity Effect by a Combination of Capsinoids and Cold Temperature Through Promoting Beige Adipocyte Biogenesis. [PDF]

, 2016
Beige adipocytes emerge postnatally within the white adipose tissue in response to certain environmental cues, such as chronic cold exposure. Because of its highly recruitable nature and relevance to adult humans, beige adipocytes have gained much ...
Bannai, Makoto, Kajimura, Shingo, Nogusa, Yoshihito, Ohyama, Kana, Shinoda, Kosaku, Suzuki, Katsuya   +5 more
core   +2 more sources

Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]

, 2020
Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D., Bell, J.D., Thomas, E.L., Thomas, E.L., Whitcher, B., Whitcher, B., Yaghootkar, H., Yaghootkar, H.   +7 more
core   +2 more sources

Control of PPARG by NOD2.

, 2023
We provide evidence here from overexpression-based gain-of-function studies in human cells (1, 2) which demonstrate control of peroxisome proliferator-activated receptor gamma, PPARG, by the NLR (nucleotide-binding oligomerization domain-like receptor) family protein NOD2.
openaire   +1 more source

Variation of PPARG Expression in Chemotherapy-Sensitive Patients of Hypopharyngeal Squamous Cell Carcinoma

PPAR Research, 2021
Our previous study showed that the upregulation of peroxisome proliferator-activated receptor gamma (PPARG) could promote chemosensitivity of hypopharyngeal squamous cell carcinoma (HSCC) in chemotherapeutic treatments.
Meng Lian, Yong Tao, Jiaming Chen, Xixi Shen, Lizhen Hou, Shaolong Cao, Jugao Fang   +6 more
doaj   +1 more source

Narrowing the wingless-2 mutation to a 227 kb candidate region on chicken chromosome 12. [PDF]

, 2018
Wingless-2 (wg-2) is an autosomal recessive mutation in chicken that results in an embryonic lethal condition. Affected individuals exhibit a multisystem syndrome characterized by absent wings, truncated legs, and craniofacial, kidney, and feather ...
Cheng, HH, Delany, ME, Gitter, CL, Kaya, M, May, B, O'Hare, EA, Webb, AE, Youngworth, IA   +7 more
core   +1 more source

MicroRNA-27b-3p Promotes Tumor Progression and Metastasis by Inhibiting Peroxisome Proliferator-Activated Receptor Gamma in Triple-Negative Breast Cancer

Frontiers in Oncology, 2020
Introduction: The role and underlying mechanisms of miR-27b-3p in triple-negative breast cancer (TNBC) remains unclear.Methods: miR-27b-3p expression level was evaluated in 99 TNBC patients with a median follow-up time of 133 months.
Song-Jie Shen, Yu Song, Xin-Yu Ren, Ya-Li Xu, Yi-Dong Zhou, Zhi-Yong Liang, Qiang Sun   +6 more
doaj   +1 more source

Perinatal, metabolic, and reproductive features inPPARG-related lipodystrophy

European Journal of Endocrinology, 2023
AbstractObjectiveThe adipogenic PPARG-encoded PPARγ nuclear receptor also displays essential placental functions. We evaluated the metabolic, reproductive, and perinatal features of patients with PPARG-related lipodystrophy.MethodsCurrent and retrospective data were collected in patients referred to a National Rare Diseases Reference Centre.Results26 ...
Gosseaume, Camille, Fournier, Thierry, Jéru, Isabelle, Vignaud, Marie-Léone, Missotte, Isabelle, Archambeaud, Françoise, Debussche, Xavier, Droumaguet, Céline, Fève, Bruno, Grillot, Sophie, Guerci, Bruno, Hieronimus, Sylvie, Horsmans, Yves, Nobécourt, Estelle, Pienkowski, Catherine, Poitou, Christine, Thissen, Jean-Paul, Lascols, Olivier, Degrelle, Séverine, Tsatsaris, Vassilis, Vigouroux, Corinne, Vatier, Camille   +21 more
openaire   +2 more sources

Anthocyanin-Containing Purple Sweet Potato (Ipomoea batatas L.) Synbiotic Yogurt Inhibited 3T3-L1 Adipogenesis by Suppressing White Adipocyte-Specific Genes

Journal of Experimental Pharmacology, 2023
Eko Fuji Ariyanto,1 Widad Aghnia Shalannandia,2 Uci Ary Lantika,3 Taufik Muhammad Fakih,4 Dwi Syah Fitra Ramadhan,5 Arini Nurisydayanti Gumilar,6 Farhan Khalil Permana,6 Anisa Nadia Rahmah,6 Nur Atik,2 Astrid Feinisa Khairani2 1Division of Biochemistry ...
Ariyanto EF, Shalannandia WA, Lantika UA, Fakih TM, Ramadhan DSF, Gumilar AN, Permana FK, Rahmah AN, Atik N, Khairani AF   +9 more
doaj  

FAM13A and POM121C are candidate genes for fasting insulin: functional follow-up analysis of a genome-wide association study [PDF]

, 2018
Aims/hypothesis: By genome-wide association meta-analysis, 17 genetic loci associated with fasting serum insulin (FSI), a marker of systemic insulin resistance, have been identified. To define potential culprit genes in these loci, in a cross-sectional
Arner, Peter, Dahlman, Ingrid, Kulyte, Agne, Lundbäck, Veroniqa, Marcus, Claude, Ryden, Mikael, Strawbridge, Rona J.   +6 more
core   +1 more source