Results 11 to 20 of about 38,455 (298)
Pparg may Promote Chemosensitivity of Hypopharyngeal Squamous Cell Carcinoma
PPAR Research, 2020 The upregulation of peroxisome proliferator-activated receptor gamma (PPARG) has been shown to increase the chemosensitivity of several human cancers. This study is aimed at studying if PPARG sensitizes hypopharyngeal squamous cell carcinoma (HSCC) in ...
Meng Lian +4 more
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Pparg signaling controls bladder cancer subtype and immune exclusion [PDF]
Nature Communications, 2021 Abstract Pparg , a nuclear receptor, is downregulated in basal subtype bladder cancers that tend to be muscle invasive and amplified in luminal subtype bladder cancers that tend to be non-muscle invasive.
Tiffany Tate +11 more
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Kernel learning for ligand-based virtual screening: discovery of a new PPARgamma agonist [PDF]
, 2010 Poster presentation at 5th German Conference on Cheminformatics: 23. CIC-Workshop Goslar, Germany. 8-10 November 2009 We demonstrate the theoretical and practical application of modern kernel-based machine learning methods to ligand-based virtual ...
Hansen, Katja +9 more
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Polymorphism of Pro12Ala and C1431T PPARγin the pathogenesis of Graves' orbitopathy
Клиническая и экспериментальная тиреоидология, 2013 AIM: to examine the association of polymorphisms Pro12Ala and C1431T PPARγwith the development of thyroid eye disease (TEO). Materials and methods. A total of 88 people: 52 patients with TEO, 36 – healthy individuals.
doaj +1 more source
PPARG as therapeutic target for antifibrotic therapy
EXCLI journal, 2020 EXCLI Journal;Vol. 19.
Ghallab, Ahmed, Seddek, Abdellatief
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PexRAP inhibits PRDM16-mediated thermogenic gene expression [PDF]
, 2017 How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Dean, John M +8 more
core +3 more sources
Вопросы современной педиатрии, 2018 Background. The genetic nature of a comorbid development of obesity and arterial hypertension (AH) in children is poorly studied. In this regard, it is important to study genes, the polymorphism of which is associated with disturbances in both metabolic ...
Olga P. Kovtun +1 more
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Variants of the human PPARG locus and the susceptibility to chronic periodontitis [PDF]
, 2011 Apart from its regulatory function in lipid and glucose metabolism, peroxisome proliferator-activated receptor (PPAR)γ has impact on the regulation of inflammation and bone metabolism.
Desvergne B +5 more
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LPS-induced Pellino3 degradation is mediated by p62-dependent autophagy [PDF]
, 2012 Background: In macrophages Toll-like receptor 4 (TLR4) is activated in response to lipopolysaccharide (LPS) and induces proinflammatory cytokine expression. Therefore, mechanisms terminating proinflammatory gene expression are important.
Brüne, Bernhard +6 more
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PPARG (peroxisome proliferator-activated receptor gamma) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on PPARG (peroxisome proliferator-activated receptor gamma), with data on DNA, on the protein encoded, and where the gene is implicated.
Astarci, E, Banerjee, S
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