Results 71 to 80 of about 1,756 (151)

Additional file 2 of Association between PPARγ, PPARGC1A, and PPARGC1B genetic variants and susceptibility of gastric cancer in an Eastern Chinese population

, 2023
Additional file 2. Supplementary Table S2.
Chen, Boyang, Wang, Yafeng, Tang, Weifeng, Chen, Yu, Liu, Chao, Kang, Mingqiang, Xie, Jinbiao   +6 more
openaire   +1 more source

PGC‐1α Activation by Polyphenols: A Pathway to Thermogenesis

Molecular Nutrition &Food Research, Volume 69, Issue 12, June 2025.
Polyphenols, derived from dietary sources such as berries, undergo digestion and interact with gut microbiota, leading to their metabolization in the liver. This process influences bile acid composition, which in turn activates PGC1α, a key regulator of mitochondrial biogenesis and thermogenesis.
Nicholas Vannuchi, Luciana Pisani
wiley   +1 more source

Extracellular vesicles from oviductal and uterine fluids supplementation in sequential in vitro culture improves bovine embryo quality

Journal of Animal Science and Biotechnology, 2022
Background In vitro production of bovine embryos is a well-established technology, but the in vitro culture (IVC) system still warrants improvements, especially regarding embryo quality.
Cláudia Lima Verde Leal, Karina Cañón-Beltrán, Yulia N. Cajas, Meriem Hamdi, Aracelli Yaryes, María Gemma Millán de la Blanca, Paula Beltrán-Breña, Rosane Mazzarella, Juliano Coelho da Silveira, Alfonso Gutiérrez-Adán, Encina M González, Dimitrios Rizos   +11 more
doaj   +1 more source

Transcriptional Profiling of SSEA‐1+ Endometrial Epithelial Progenitor Cells Highlights Their Role in Endometrial Regeneration, Remodeling, and Homeostasis

The FASEB Journal, Volume 39, Issue 9, 15 May 2025.
Sampling, isolation, cell sorting and microarray analysis of SSEA‐1+ endometrial epithelial progenitor cells. Gene expression data was analysed using computational pathway analysis methods and internally validated using real‐time quantitative PCR and externally validated using dual‐label immunofluorescence and endometrial epithelial organoid models ...
Hannan Al‐Lamee, Jamie Soul, Daniel Green, Josephine Drury, Christopher J. Hill, Olga Vasieva, Anthony Valentijn, Alison Maclean, Andrew Drakeley, Nicola Tempest, Dharani K. Hapangama   +10 more
wiley   +1 more source

A Comprehensive Review on LncRNAs/miRNAs‐DNMT1 Axis in Human Cancer: Mechanistic and Clinical Application

Journal of Cellular and Molecular Medicine, Volume 29, Issue 10, May 2025.
ABSTRACT Cancer constitutes a significant public health concern, and addressing the challenge of cancer holds paramount importance and requires immediate attention. Epigenetic alterations, encompassing DNA methylation, have emerged as pivotal contributors to the development of diverse cancer types.
Seyed Mohsen Aghaei‐Zarch, Ali Esmaeili, Saeid Bagheri‐Mohammadi   +2 more
wiley   +1 more source

Oxidative stress‐induced changes in wooden breast and mitigation strategies: A review

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 2, March 2025.
Abstract Wooden breast (WB) is a multifactorial muscular abnormality resulting from the interplay between genetic predispositions for rapid growth, physiological stress, and anatomical impairments. This myopathy has been a persistent challenge in the poultry industry since its initial identification a decade ago.
Yaqin Wang, Binbin Li, Ching Jian, Mohammed Gagaoua, Mario Estévez, Eero Puolanne, Per Ertbjerg   +6 more
wiley   +1 more source

Neuro‐Immunomodulatory Potential of Nanoenabled 4D Bioprinted Microtissue for Cartilage Tissue Engineering

Advanced Healthcare Materials, Volume 14, Issue 5, February 18, 2025.
4D‐bioprinted HCM nanoenabled with ibuprofen‐PLGA nanoparticles is presented. In an in vitro inflamed environment, nanoenabled HCM reduced IL‐1β and IL‐6 release and maintained ECM production, and in vivo, its secretome reduced dendritic cell recruitment, and inflammatory mediators, with no impact on nerve sprouting, indicating neuro‐immunomodulatory ...
Marina Couto, Daniela Pereira Vasconcelos, Catarina Leite Pereira, Estrela Neto, Bruno Sarmento, Meriem Lamghari   +5 more
wiley   +1 more source

Genetic Landscape of Obesity in Children: Research Advances and Prospects

Journal of Obesity, Volume 2025, Issue 1, 2025.
Obesity is a chronic metabolic disease characterized by excessive accumulation or uneven distribution of fat in the body, which poses a serious threat to health. Obesity significantly increases the risk of developing сonditions such as type 2 diabetes, coronary heart disease, hypertension, obstructive sleep apnea, and some types of cancer.
Rita Khusainova, Ildar Minniakhmetov, Olga Vasyukova, Bulat Yalaev, Ramil Salakhov, Darya Kopytina, Raisat Guseinova, Ekaterina Dobreva, Galina Melnichenko, Ivan Dedov, Natalia Mokrysheva, Claire Stocker   +11 more
wiley   +1 more source

PPARGC1B: insight into the expression of the gouty inflammation phenotype [PDF]

Rheumatology, 2016
Tony, Merriman, Robert, Terkeltaub
openaire   +2 more sources

Chronic ethanol consumption disrupts the core molecular clock and diurnal rhythms of metabolic genes in the liver without affecting the suprachiasmatic nucleus.

PLoS ONE, 2013
Chronic ethanol consumption disrupts several metabolic pathways including β-oxidation and lipid biosynthesis, facilitating the development of alcoholic fatty liver disease.
Ashley N Filiano, Telisha Millender-Swain, Russell Johnson, Martin E Young, Karen L Gamble, Shannon M Bailey   +5 more
doaj   +1 more source