Results 61 to 70 of about 1,756 (151)

Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu, Na Zhang, Zilong Wen, Haitao Wang, Tingting Li, Runlin Ma, Menghua Li, Daxiang Wang, Haiping Shu, Xun Huang, Jianlin Han, Yiqiang Zhao, Qiuyue Liu   +12 more
wiley   +1 more source

THE ASSOCIATION OF GENE POLYMORPHISMS WITH ATHLETE STATUS IN UKRAINIANS

Biology of Sport, 2013
Athletic performance is a polygenic trait influenced by both environmental and genetic factors. Objective: to investigate individually and in combination the association of common gene polymorphisms with athlete status in Ukrainians.
Svitlana B. Drozdovska, Victor E. Dosenko, Ildus I. Ahmetov, Vladimir N. Ilyin   +3 more
doaj   +1 more source

Additional file 3 of Association between PPARγ, PPARGC1A, and PPARGC1B genetic variants and susceptibility of gastric cancer in an Eastern Chinese population

, 2023
Additional file 3. Supplementary Table S3.
Chen, Boyang, Wang, Yafeng, Tang, Weifeng, Chen, Yu, Liu, Chao, Kang, Mingqiang, Xie, Jinbiao   +6 more
openaire   +1 more source

Targeting the Liver Serine Protease TMPRSS6 Ameliorates Steatosis and Attenuates Fibrosis in Experimental MASLD

Liver International, Volume 45, Issue 7, July 2025.
ABSTRACT Background and Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common cause of liver disease and a leading contributor to liver‐related morbidity and mortality. Currently, no pharmacological approach has demonstrated consistent and long‐lasting benefits across all patients.
Mariateresa Pettinato, Valeria Furiosi, Rossana Carleo, Letizia Bavuso Volpe, Shuling Guo, Valeria Mannella, Giovanna Musco, Enrica Gilberti, Giuseppe De Palma, Giorgia Federico, Francesca Carlomagno, Alessandro Cherubini, Serena Pelusi, Anxhela Dano, Antonella Nai, Luca Valenti, Sandro Altamura, Alessia Pagani, Laura Silvestri   +18 more
wiley   +1 more source

Dose threshold for radiation induced fetal programming in a mouse model at 4 months of age: Hepatic expression of genes and proteins involved in glucose metabolism and glucose uptake in brown adipose tissue.

PLoS ONE, 2020
Exposure to ionizing radiation contributing to negative health outcomes is a widespread concern. However, the impact of low dose and sub-lethal dose radiation (SLDR) exposures remain contentious, particularly in pregnant women who represent a vulnerable ...
Caitlund Q Davidson, Sujeenthar Tharmalingam, Sarah Niccoli, Ashley Nemec-Bakk, Sandhya Khurana, Alyssa Murray, T C Tai, Douglas R Boreham, Neelam Khaper, Simon J Lees   +9 more
doaj   +1 more source

Additional file 4 of Association between PPARγ, PPARGC1A, and PPARGC1B genetic variants and susceptibility of gastric cancer in an Eastern Chinese population

, 2023
Additional file 4. Supplementary Table S4.
Chen, Boyang, Wang, Yafeng, Tang, Weifeng, Chen, Yu, Liu, Chao, Kang, Mingqiang, Xie, Jinbiao   +6 more
openaire   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, Volume 19, Issue 6, Page 1687-1706, June 2025.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Maternal dietary methionine restriction alters the expression of energy metabolism genes in the duckling liver

BMC Genomics, 2022
Background In mammals, the nutritional status experienced during embryonic development shapes key metabolic pathways and influences the health and phenotype of the future individual, a phenomenon known as nutritional programming. In farmed birds as well,
Aurélie Sécula, Hervé Chapuis, Anne Collin, Lisa E. Bluy, Agnès Bonnet, Loys Bodin, Laure Gress, Alexis Cornuez, Xavier Martin, Cécile M. D. Bonnefont, Mireille Morisson   +10 more
doaj   +1 more source

Additional file 1 of Association between PPARγ, PPARGC1A, and PPARGC1B genetic variants and susceptibility of gastric cancer in an Eastern Chinese population

, 2023
Additional file 1. Supplementary Table S1.
Chen, Boyang, Wang, Yafeng, Tang, Weifeng, Chen, Yu, Liu, Chao, Kang, Mingqiang, Xie, Jinbiao   +6 more
openaire   +1 more source

Ageing Signatures and Disturbed Muscle Regeneration in Muscle Proteome of Inclusion Body Myositis

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.
ABSTRACT Background Inclusion body myositis (IBM) is the most common acquired myopathy in adults over the age of 50 years, characterised by inflammatory and degenerative features that lead to progressive muscle weakness and physical disability for lack of effective therapies.
Geert M. de Vries, Bob Asselbergh, Alice Monticelli, Peter De Jonghe, Stuart Maudsley, Peter Y. K. Van Den Bergh, Anne Bigot, Jan L. De Bleecker, Biljana Ermanoska, Willem De Ridder, Jonathan Baets   +10 more
wiley   +1 more source