Gastrointestinal Manifestations in Rubinstein‐Taybi Syndrome
ABSTRACT Rubinstein–Taybi syndrome is a rare genetic condition associated with a wide range of physical, cognitive, and developmental impairments, yet its gastrointestinal manifestations remain poorly characterized. Case reports and small series suggest a high prevalence of gastroesophageal reflux, constipation, dysphagia, and nutritional compromise ...
Mohamad Abi Nassif +3 more
wiley +1 more source
Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding +10 more
wiley +1 more source
A comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster
This study presents the first comprehensive proteome and phosphoproteome atlas of the Chinese hamster across nine organs (heart, liver, lung, kidney, spleen, cerebral cortex, skeletal muscle, stomach, and testis or ovary). A total of 14 219 proteins were identified in the proteome, with 11 828 phosphorylated proteins and 47 122 phosphorylation sites ...
Luyao Zhang +15 more
wiley +1 more source
Impact of proton pump inhibitors on immunotherapy is modulated by prior chemotherapy and linked to gut microbiome-immune cell signatures. [PDF]
Petouhoff A +27 more
europepmc +1 more source
GP perspectives on a computer-assisted strategy to support PPI deprescribing: a qualitative study. [PDF]
Kornder N +10 more
europepmc +1 more source
Takotsubo syndrome in the setting of cardiac pacing: A review of mechanistic and clinical perspectives. [PDF]
Yalta K, Ozkan U, Yetkin E.
europepmc +1 more source
Appropriate prescribing and deprescribing of proton pump inhibitors: New Choosing Wisely Canada toolkit. [PDF]
Bland E, van Zanten SV, Thompson W.
europepmc +1 more source
Microsecond Dynamics of the Pyrophosphate Ion Release in SARS-CoV‑2 RNA Polymerase. [PDF]
Xu T +8 more
europepmc +1 more source

