Results 11 to 20 of about 280,167 (308)

Protonenpumpenhemmer (PPI) in Deutschland: Status Quo eines wachsenden Marktes

open access: yesMonitor Versorgungsforschung
Das Verschreibungsvolumen von Protonenpumpeninhibitoren (PPI) ist nach wie vor hoch, obwohl in der Literatur zunehmend darauf hingewiesen wird, dass in Relation zu den Leitlinienempfehlungen eine übermäßige Verschreibung erfolgt.
Monika Häring   +2 more
doaj   +2 more sources

PPI-based MR simulation script

open access: yes, 2022
R script to run PPI-based MR simulations. Using a SNP-to-Gene dictionary, simulated clusters of gene-derived SNPs are used as IVs for MR to estimate the false discovery rate of PPI-based MR with respect to a given pair of exposure and outcome summary ...
Jessica Kain (13876949)
core   +1 more source

Native mass spectrometry guided screening identifies hit fragments for HOP-HSP90 PPI inhibition [PDF]

open access: yes, 2021
Contemporary medicinal chemistry considers fragment-based drug discovery (FBDD) and inhibition of Protein-Protein Interactions (PPI), as important means of expanding druggable chemical space.
C. Logan, Mackay   +6 more
core   +1 more source

Comprehensive Human PPI Network and TF Network

open access: yes, 2022
A public resource for curated and comprehensive high-quality PPI network data. The benefit of such a public data resource allows additional information to be integrated based on research question.
Srinivasan, Suhas
core   +1 more source

PPI-Affinity: A Web Tool for the Prediction and Optimization of Protein–Peptide and Protein–Protein Binding Affinity

open access: yes, 2022
Virtual screening of protein–protein and protein–peptide interactions is a challenging task that directly impacts the processes of hit identification and hit-to-lead optimization in drug design projects involving peptide-based pharmaceuticals.
Michael Ehrmann (2154331)   +6 more
core   +2 more sources

Phosphonium-substituted Diphosphaindenylide (PPI): Exploration of Biradical Character and Ligand Properties [PDF]

open access: yes, 2023
Starting from C6H4(PCl2)2 and the TMS-substituted ylide (TMS)2C=PR3 (TMS = trimethylsilyl, R = p-tolyl), the phosphonium-substituted diphosphaindenylide PPI was prepared in two steps.
Clara, Schweinzer   +2 more
core   +2 more sources

PPI-Miner: A Structure and Sequence Motif Co-Driven Protein–Protein Interaction Mining and Modeling Computational Method

open access: yes, 2022
Protein–protein interactions (PPIs) play important roles in biological processes of life, and predicting PPIs becomes a critical scientific issue of concern. Most PPIs occur through small domains or motifs (fragments), which are challenging and laborious
Feng-lei Li (14196110)   +4 more
core   +1 more source

When participants get involved: reconsidering patient and public involvement in clinical trials at the MRC Clinical Trials Unit at UCL

open access: yesTrials, 2018
Background Patient and public involvement (PPI) in clinical trials aims to ensure that research is carried out collaboratively with patients and/or members of the public.
Claire L. Vale   +7 more
doaj   +1 more source

MEDIATING EFFECT OF BRAND IMAGE AND BRAND TRUST BETWEEN E-WOM ON SMARTPHONE BUY INTEREST IN TANGERANG CITY

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2021
The population in this study is the people in Tangerang City who are at least 17 years old and know about smartphone products. The sample was taken by 150 respondents using purposive sampling.
Dewi F.M., Sulivyo L., Bastaman A.
doaj   +1 more source

Macrophage-Related Genes Biomarkers in Left Ventricular Remodeling Induced by Heart Failure

open access: yesReviews in Cardiovascular Medicine, 2022
Background: Elevated left ventricular mass index contributes to morbidity and mortality induced by heart failure and M2 macrophages play a critical role in left ventricular remodeling.
Yue Zheng   +6 more
doaj   +1 more source

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