Results 51 to 60 of about 94,951 (115)

Pyrroloquinoline quinone protects heat-stressed porcine oocytes and improves early embryonic development via maintaining mitochondrial integrity and redox homeostasis

Biology Direct
Heat stress (HS) is a major environmental factor that impairs female fertility by disrupting oocyte quality and developmental competence. Pyrroloquinoline quinone (PQQ), a redox cofactor with strong antioxidant and mitochondrial-protective properties ...
Mianqun Zhang, Qimei Xu, Bo Jia, Xue Zhang, Khienduc Lay, Mengchan Li, Yan Zou, Ziyi Wang, Xu Peng, Yang Gao, Changyin Zhou, Yanfeng Xue, Yunhai Zhang   +12 more
doaj   +1 more source

Molecular Mechanisms of Plant Growth–Promoting Rhizobacteria (PGPR) in Biofertilization and Disease Suppression of Crops

International Journal of Agronomy, Volume 2026, Issue 1, 2026.
Plant growth–promoting rhizobacteria (PGPR) are beneficial soil bacteria that colonize the rhizosphere and enhance plant growth through direct and indirect mechanisms, including nutrient solubilization, phytohormone production, suppression of phytopathogens, and activation of plant defense mechanisms.
Etsay Mesele, Gebremedhin Gebreslassie, Ashenafi Teklay Yaekob, Tesfakiros Semere, Maria Serrano   +4 more
wiley   +1 more source

Portable multimodal sensing system for screening of diabetes mellitus from human urine

VIEW, Volume 6, Issue 5, October 2025.
A compact multimodal sensing device was developed for the simultaneous detection of glucose and acetone from urine samples. Combining electrochemical and gas sensors, the device demonstrates reliable performance within clinically relevant ranges. This portable system offers a holistic metabolic assessment, supporting early screening of diabetes and ...
Mario Soto Martinez, Yurii Tsyban, Alexander Przybysz, Abdullah Bukhamsin, Yuvaraj Sivalingam, Khaled Nabil Salama   +5 more
wiley   +1 more source

Pyrroloquinoline Quinone Mitigates Testicular Injury and Reduces Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in Rats with Testicular Ischemia–Reperfusion Injury

Antioxidants
Testicular torsion–detorsion (T/D) induces ischemia–reperfusion injury, leading to mitochondrial dysfunction, oxidative stress, apoptosis, and spermatogenic impairment.
Syuan-Hao Syu, Chao-Yuan Chang, Hung-Jen Shih, Chun-Jen Huang   +3 more
doaj   +1 more source

High-affinity PQQ import is widespread in Gram-negative bacteria

bioRxiv
PQQ is a soluble redox cofactor used by diverse bacteria to oxidise fuel compounds as a source of electrons for the respiratory chain. Many Gram-negative bacteria that encode PQQ-dependent enzymes do not possess the biosynthetic machinery for its ...
Fabian Munder, Marcos Y. Voutsinos, Klaus Hantke, H. Venugopal, R. Grinter   +4 more
semanticscholar   +1 more source

Pyrroloquinoline quinone targets senescent osteoclasts and reduces spinal pain and endplate degeneration in a lumbar spine instability mouse model

Journal of Translational Medicine
Background Pyrroloquinoline Quinone (PQQ) is a redox cofactor with potent antioxidant and anti-inflammatory properties. This study investigated the therapeutic potential of PQQ in alleviating spinal pain and degeneration in a lumbar spine instability ...
Qinghe Geng, Yan Geng, Ke Heng, Juan Zhai, Xingchen Song, Liangwei Sha, Yinuo Geng, Peiru Nie, Fanshuo Liu, Huaiyuan Zhai, Junli Huang, Yanhong Liu, Mei Li, Guoqiang Wang, Rui Geng, Kui Xue, Qilong Wang, Wanying Huang, Shuangshuang Suo, Huanyu Zhang, Ying Geng, Yuanji Yang, Junyun Lan, Hengsheng Hu, Shengnan Liu, Xiangfei Meng, Yilong Guo, Jie Li   +27 more
doaj   +1 more source

PQQ ameliorates D-galactose induced cognitive impairments by reducing glutamate neurotoxicity via the GSK-3β/Akt signaling pathway in mouse

Scientific Reports, 2018
Oxidative stress is known to be associated with various age-related diseases. D-galactose (D-gal) has been considered a senescent model which induces oxidative stress response resulting in memory dysfunction.
Xing-qin Zhou, Zhi-wen Yao, Ying-Fu Peng, S. Mao, Dong Xu, X. Qin, Rong Zhang   +6 more
semanticscholar   +1 more source

Interactions of rare earth elements with living organisms and emerging biotechnical applications

PLANTS, PEOPLE, PLANET, Volume 7, Issue 5, Page 1251-1274, September 2025.
Rare earth elements (REEs) are critical resources required to achieve net‐zero carbon emission targets and energy security. However, rising demand for REEs coupled with significant extraction and processing challenges and geopolitical risks restricts access to REE resources.
Samantha A. McGaughey, Shagufta Iqbal, Annamaria De Rosa, Jessica A. Caley, Anna H. Kaksonen, Denys Villa‐Gomez, Caitlin S. Byrt   +6 more
wiley   +1 more source

Pyrroloquinoline Quinone (PQQ) and Rheumatic Diseases

International Journal of Medical Science and Pharmaceutical Research
Introduction: Pyrroloquinoline quinone (PQQ) is a redox cofactor with antioxidant and immunomodulating actions implicated in protection of mitochondria and modulation of inflammation pathways.
Jozélio Freire de Carvalho, MD, PhD
semanticscholar   +1 more source

Pyrroloquinoline Quinone Is an Effective Senomorphic Agent to Target the Pro‐Inflammatory Phenotype of Senescent Cells

Aging Cell, Volume 24, Issue 9, September 2025.
As a natural senomorphic agent, PQQ targets the intracellular molecule. HSPA8 of senescent cells, resulting in significantly reduced expression of the SASP. PQQ holds prominent potential to delay chronological aging and ameliorate age‐related conditions by acting as an effective senomorphic agent.
Birong Jiang, Hongwei Zhang, Qixia Xu, Zhirui Jiang, Ruikun He, Qiang Fu, Yu Sun   +6 more
wiley   +1 more source