Results 111 to 120 of about 468,258 (305)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Contextuality in Practical Reason [book review]

open access: yes, 2009
Este artículo reseña: Price, A. W. Contextuality in Practical Reason. Oxford: Oxford University Press, 2008.
Gaitán Torres, Antonio   +2 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Practical reason

open access: yes, 1953
I shall be concerned in this essay to say something about morality. Of necessity therefore I shall be saying something about action. When a person acts he expresses his will.
Robinson, Erle Burdett
core  

Purity and Practical Reason: On Pragmatic Genealogy

open access: yesErgo, An Open Access Journal of Philosophy, 2023
Nicholas Smyth
doaj   +2 more sources

The Relation between Rational Perfection (Unification with Active Intellect) and Moral Perfection, in the Mulla Sadra’s View [PDF]

open access: yesحکمت معاصر, 2015
The role of science and action in achieving perfection and beatitude is very notable and has very special and important place in Mulla Sadra’s view. Sadra’s phrases show that achieving rational perfection which involves unionization with active intellect
Seyyed Morteza Hoseini Shahrudi   +1 more
doaj  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Practical Reason

open access: yes
Kiesewetter B, Wallace RJ. Practical Reason.
Kiesewetter, Benjamin ; https://orcid.org/   +1 more
core  

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