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The use of electronic voting and peer assessment to encourage the development of higher order thinking skills in learners [PDF]
In the research reported here, electronic voting and peer assessment were used with 215 first year computer science and information technology undergraduates undertaking an electronic media design module.
Barker, Trevor, Bennett, Steve
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Natural Law: A legacy of Veritatis Splendor
The encyclical of Saint John Paul II constitutes a milestone in the history of the Church: it is the first time that the Magisterium dedicated a document to address the doctrinal foundations of moral theology.
María Soledad Paladino
doaj +3 more sources
Mysticism and Practical Rationality Exploring Evelyn Underhill through the Lens of Phronesis
This paper aims to justify that mysticism can be considered rational from the perspective of practical reason. Particularly, we will argue that mysticism embodies the oxymoron inherent in practical wisdom (phronesis), namely, an ordered openness.
Diego Pérez Lasserre
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
An Instrumentalist Account of How to Weigh Epistemic and Practical Reasons for Belief [PDF]
When one has both epistemic and practical reasons for or against some belief, how do these reasons combine into an all-things-considered reason for or against that belief?
Skipper, Mattias +1 more
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Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Case for Growth: Why Measure Student Learning? [PDF]
A fundamental question -- perhaps the fundamental question -- educators ask is, "Are my students learning?" Many educators choose to gain key information from assessments that measure student achievement and growth, and for good reason: just as you might
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