Results 71 to 80 of about 5,580,867 (303)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Practical Action Sudan Annual Highlights 2007-8

open access: yes, 2008
Highlights of Practical Action's work in Sudan, 2007-
Practical Action Sudan
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

On practical ℎ-observer design for nonlinear non-autonomous dynamical systems with disturbances [PDF]

open access: yesArchives of Control Sciences
In this paper, a particular form of practical ℎ-observers for piecewise continuous Lipschitz, one-sided piecewise continuous Lipschitz systems and quasi-one-sided piecewise continuous Lipschitz systems is extended to nonlinear non-autonomous dynamical ...
Manel Alaya   +3 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Practical stability of linear switched impulsive system with time delay

open access: yesElectronic Journal of Differential Equations, 2014
This article concerns the study of practical stability of linear switched impulsive systems with time delay. By using Lyapunov functions and the extended Halanay inequality, we establish sufficient conditions for the practical stability and uniform ...
Shao'e Li, Weizhen Feng
doaj  

Further results on finite time and practical stability of linear continuous time delay systems [PDF]

open access: yesFME Transactions, 2013
In this paper, finite-time stability and practical stability problems for a class of linear continuous time-delay systems are studied. Based on the Lyapunov-like functions, that do not have to be positive definite in the whole state space and not need to
Debeljković Dragutin Lj.   +2 more
doaj  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Stability of Natural Systems – Theory and Practice [PDF]

open access: yesMiscellanea Geographica, 2008
Abstract The article discusses definitions and origin of the term “stability”. A difference is made between the stability of systems and their equilibrium. Practical and theoretical application of the term and limitations of its application are presented.
openaire   +3 more sources

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