Results 91 to 100 of about 468,747 (306)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Further results on finite time and practical stability of linear continuous time delay systems [PDF]
FME Transactions, 2013 In this paper, finite-time stability and practical stability problems for a class of linear continuous time-delay systems are studied. Based on the Lyapunov-like functions, that do not have to be positive definite in the whole state space and not need to
Debeljković Dragutin Lj. +2 more
doaj
AxiomsWe investigate the stability of linear discrete-time control systems with a fuzzy logic feedback under sporadic sensor data loss. In our framework, each state measurement is a fuzzy number, and occasional “packet dropouts” are modeled by a lacunary ...
Muhammed Recai Türkmen +1 more
doaj +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Stability of Natural Systems – Theory and Practice [PDF]
Miscellanea Geographica, 2008 Abstract The article discusses definitions and origin of the term “stability”. A difference is made between the stability of systems and their equilibrium. Practical and theoretical application of the term and limitations of its application are presented.
openaire +3 more sources
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Practical ϕ0-stability of impulsive dynamic systems on time scales
, 2007 In this work, some criteria for practical ϕ0-stability and strongly practical ϕ0-stability of impulsive dynamic systems on time scales are ...
Wang, Peiguang, Wu, Meng
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source