Results 111 to 120 of about 1,365,427 (315)

Development of a novel algorithm to determine adherence to chronic pain treatment guidelines using administrative claims

open access: yesJournal of Pain Research, 2017
Jay M Margolis,1 Nicole Princic,2 David M Smith,2 Lucy Abraham,3 Joseph C Cappelleri,4 Sonali N Shah,5 Peter W Park5 1Truven Health Analytics, Bethesda, MD, 2Truven Health Analytics, Cambridge, MA, USA; 3Pfizer Ltd, Tadworth, UK; 4Pfizer Inc, Groton, CT,
Margolis JM   +6 more
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Exames radiográficos solicitados no atendimento inicial de pacientes em uma Faculdade de Odontologia brasileira

open access: yesRevista de Odontologia da UNESP
INTRODUÇÃO: Para que radiografias ofereçam mais benefícios do que riscos, precisam ser realizadas ou solicitadas de acordo com cada situação clínica.OBJETIVO: Avaliar os exames radiográficos solicitados no atendimento inicial em uma Faculdade de ...
Lucas Borin MOURA   +2 more
doaj   +1 more source

NICEly does it: economic analysis within evidence-based clinical practice guidelines [PDF]

open access: yes
There is increasing professional and policy interest in the role of clinical guidelines for promoting effective and efficient health care. The NHS Health Technology Assessment Programme identified an urgent need, when such guidelines are produced, to ...
Nick Freemantle   +3 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Guidelines on Performing Prostate Biopsy. Systematic development of clinical practice guidelines for prostate biopsies: a 3-year Italian project.

open access: yes, 2007
BACKGROUND: The only available method to detect prostate cancer is prostate biopsy; however, to our knowledge, no evidence-based clinical practice guidelines have been established on this topic.
PRAYER GALETTI T   +9 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

The revised recommendation for administering vitamin C in septic patients: The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020

open access: yesAcute Medicine & Surgery, 2022
Guideline Committee of The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020
doaj   +1 more source

Guidelines on Investigating Violations of International Humanitarian Law: Law, Policy, and Good Practice [PDF]

open access: yes, 2019
Investigations into alleged violations of international humanitarian law by the parties to an armed conflict are not only crucial to securing respect for IHL, but also to preventing future violations and enabling redress for victims of past violations ...
Lubell, Noam   +2 more
core  

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