Results 101 to 110 of about 1,214,653 (312)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Special Article: One Resident\u27s Perspective on a Different Style of Psychopharmacological Practice [PDF]
, 2011 This article provides a comparison of psychopharmacological practices in the U.S. and France. The prescription as well as proscription of various classes of psychotropic drugs are considered.
Amiel, M.D., Michael +1 more
core +1 more source
Patients' experiences of seeking help for emotional concerns in primary care: doctor as drug, detective and collaborator [PDF]
, 2020 Background NICE guidelines for the management of emotional concerns in primary care emphasise the importance of communication and a trusting relationship, which is difficult to operationalise in practice.
Byng, R. +3 more
core +4 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Joint statement on evidence-based practices in mechanical ventilation: suggestions from two Brazilian medical societies [PDF]
Jornal Brasileiro de PneumologiaMechanical ventilation can be a life-saving intervention, but its implementation requires a multidisciplinary approach, with an understanding of its indications and contraindications due to the potential for complications.
Juliana Carvalho Ferreira +5 more
doaj +1 more source
2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery
British Journal of AnaesthesiaPreamble Clinical practice guidelines consolidate and evaluate all pertinent evidence on a specific topic available at the time of their formulation. The goal is to assist physicians in determining the most effective management strategies for patients ...
Alexander Wahba +39 more
semanticscholar +1 more source
Promoting game accessibility: Experiencing an induction on inclusive design practice at the global games jam [PDF]
, 2013 Copyright @ 2013 The AuthorsThe Global Games Jam (GGJ) attracts many people who are passionate about games development, coming from a range of educational backgrounds.
Ghinea, G, Scott, M
core +3 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Current approach for the prosthesis patient mismatch
Türk Kardiyoloji Derneği Arşivi, 2013 All prosthetic valves are at least mildly stenotic and have relatively high transvalvular pressure gradients that can be observed despite normal prosthesis function.
Asuman Biçer Yeşilay +2 more
doaj +1 more source
Consultation on changes to the academic infrastructure [PDF]
, 2010 "Th[e consultation] document sets out the proposals of the Quality Assurance Agency for Higher Education (QAA) for restructuring the Academic Infrastructure to address the findings of an evaluation completed in summer 2010. Overall, the results of the
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