Results 11 to 20 of about 79,378 (235)

How can health economics be used in the design and analysis of adaptive clinical trials? A qualitative analysis [PDF]

open access: yes, 2020
Introduction Adaptive designs offer a flexible approach, allowing changes to a trial based on examinations of the data as it progresses. Adaptive clinical trials are becoming a popular choice, as the prudent use of finite research budgets and accurate ...
Brennan, Alan   +4 more
core   +2 more sources

Disentangling syntactic, semantic and pragmatic impairments in ASD : elicited production of passives [PDF]

open access: yes, 2021
Children with ASD and an IQ-matched control group of typically developing (TD) children completed an elicited-production task which encouraged the production of reversible passive sentences (e.g., “Bob was hit by Wendy”).
Ambridge, B, Bidgood, A, Thomas, K
core   +3 more sources

Electronic health records to facilitate clinical research [PDF]

open access: yes, 2016
Electronic health records (EHRs) provide opportunities to enhance patient care, embed performance measures in clinical practice, and facilitate clinical research. Concerns have been raised about the increasing recruitment challenges in trials, burdensome
Blomster, Juuso I.   +17 more
core   +2 more sources

A roadmap to develop dementia research capacity and capability in Pakistan: a model for low- and middle-income countries [PDF]

open access: yes, 2019
Objective To produce a strategic roadmap for supporting the development of dementia research in Pakistan. Background While global research strategies for dementia research already exist, none is tailored to the specific needs and challenges of low ...
Ambily Sathish   +28 more
core   +1 more source

Communication difficulties following right hemisphere stroke : applying evidence to clinical management [PDF]

open access: yes, 2008
Following reports in the 1960s that language may be affected by right hemisphere (RH) lesions, many limitations to effective communication in the right hemisphere damaged (RHD) population have been described and evidenced.
Brady, Marain, Mackenzie, Catherine
core   +1 more source

Clinical trial metadata:Defining and extracting metadata on the design, conduct, results and costs of 125 randomised clinical trials funded by the National Institute for Health Research Health Technology Assessment programme [PDF]

open access: yes, 2015
Background:  By 2011, the Health Technology Assessment (HTA) programme had published the results of over 100 trials with another 220 in progress. The aim of the project was to develop and pilot ‘metadata’ on clinical trials funded by the HTA programme.  
Cook, Andrew   +6 more
core   +2 more sources

Purity or pragmatism? : Reflecting on the use of systematic review methodology in development [PDF]

open access: yes, 2012
Systematic review methodology pioneered in health care has been increasingly applied to development questions of importance in lower- and middle-income countries.
de Wet, Thea   +2 more
core   +2 more sources

Choosing and using methodological search filters : searchers' views [PDF]

open access: yes, 2015
© 2014 The authors.
Beale, Sophie   +10 more
core   +1 more source

“It’s trying to manage the work” : A qualitative evaluation of recruitment processes within a UK multi-centre trial [PDF]

open access: yes, 2017
Acknowledgments The authors would like to thank all interviewees who agreed to take part in this study. The authors would like to thank the TISU Trial Group for their support with this project. In particular, the authors would like to thank Sarah Cameron
Gillies, Katie   +2 more
core   +1 more source

Setting priorities to inform assessment of care homes’ readiness to participate in healthcare innovation: a systematic mapping review and consensus process [PDF]

open access: yes, 2020
© 2020 The Author(s). This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly citedOrganisational ...
Bunn, F.   +8 more
core   +4 more sources

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