Results 61 to 70 of about 79,378 (235)

Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation

Health Technology Assessment
Background High-risk patients with complex anorexia nervosa are managed in inpatient/day patient care, but re-admission rates are high, and new treatments are needed.
Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau   +12 more
doaj   +1 more source

A unified framework for building ontological theories with application and testing in the field of clinical trials [PDF]

, 2001
The objective of this research programme is to contribute to the establishment of the emerging science of Formal Ontology in Information Systems via a collaborative project involving researchers from a range of disciplines including philosophy, logic ...
Barbara, Heller, Heinrich, Herre, Smith, Barry   +2 more
core   +1 more source

How should we evaluate research on counselling and the treatment of depression? A case study on how NICE’s draft 2018 guideline considered what counts as best evidence [PDF]

, 2017
Background: Health guidelines are developed to improve patient care by ensuring the most recent and “best available evidence” is used to guide treatment recommendations (NICE Guidance, 2017).
Barber, Barkham, Barkham, Barkham, Barnes, Barth, Beattie, Beck, Bedi, Binder, Cape, Cartwright, Clark, Clarke, Cohen, Cuijpers, Cuijpers, Cuijpers, Cuijpers, Emslie, Evans, Goldman, Greenberg, Gyani, Gyani, Hernandez-Villafuerte, Hill, Hussain-Gambles, Jadad, Kanters, Kaufman, Kazdin, Kennedy-Martin, King, Kroenke, Lawrence, Lawrence, Levitt, Lillevoll, Lindhiem, London School of Economics and Political Science. Centre for Economic Performance. Mental Health Policy Group, Mason, McLeod, Midgley, Mills, Moriana, Mundt, Nilsson, Perren, Pybis, Radhakrishnan, Rawlins, Ridge, Roth, Sanders, Saxon, Saxon, Saxon, Simpson, Smith, Spitzer, Stiles, Stiles, Stoppard, Straarup, Stronks, Stuart, Timulak, Valkonen, Vlayen, Wald, Ward, Watson, Wessley, Williams   +74 more
core   +2 more sources

Swallowing and Communication in Cockayne Syndrome: Clinical Characteristics and Management

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cockayne syndrome (CS) is an ultrarare genetic disorder associated with genes encoding proteins involved in DNA repair. The clinical course of CS involves neurodevelopmental and neurodegenerative features, including swallowing and communication impairments.
Abigail M. Spoden, Katlyn E. McGrattan, Peter B. Kang   +2 more
wiley   +1 more source

Internet and telephone intervention to support patients discontinuing long-term antidepressants in primary care: the REDUCE research programme including RCT

Programme Grants for Applied Research
Background There is significant concern about increasing long-term antidepressant use in Western countries, much of which is not evidence-based. Median duration of treatment is more than 2 years in the United Kingdom, and more than 10% of adults are ...
Tony Kendrick, Beth Stuart, Hannah Bowers, Mahboobeh Haji Sadeghi, Helen Page, Christopher Dowrick, Michael Moore, Mark Gabbay, Geraldine Leydon, Guiqing Lily Yao, Shihua Zhu, Paul Little, Gareth Griffiths, Glyn Lewis, Carl May, Joanna Moncrieff, Chris F Johnson, Una Macleod, Simon Gilbody, Rachel Dewar-Haggart, Samantha Williams, Wendy O’Brien, Riya Tiwari, Catherine Woods, Tasneem Patel, Naila Khan, Emma Maund, Nadja van Ginneken, Amy Din, Claire Reidy, Rebecca Lucier, Bryan Palmer, Taeko Becque, Yumna Masood, Natalie Thompson, Ellen van Leeuwen, Marta Glowacka, Adam WA Geraghty   +37 more
doaj   +1 more source

Meeting update: faecal microbiota transplantation––bench, bedside, courtroom? [PDF]

, 2016
A group of stakeholders met, under the aegis of the British Society of Gastroenterology, to discuss the current landscape of faecal microbiota transplant- ation (FMT) within the UK and beyond.
Ding, N, Hart, A, Marchesi, J, McLaughlin, J, Mullish, BH   +4 more
core   +1 more source

Remote Language Assessment in School‐Age Children With Phelan–McDermid Syndrome and Genotype–Phenotype Correlation

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT People with Phelan–McDermid syndrome (PMS) have reduced speech and language abilities, yet little research has profiled the communication abilities in this population. The purpose of this study was threefold: identifying the language and communication profiles of school‐aged children with PMS, identifying genetic contributions to language and ...
Sarah Quadri‐Valverde, Jessica Klusek, Linda D. Ward, Diana Ivankovic, Nancy Powers, Vijay Shankar, Rachel A. Lyman, Trudy F. C. Mackay, William Bridges, Katy Phelan, Curtis Rogers, Luigi Boccuto, Sara M. Sarasua   +12 more
wiley   +1 more source

Low-dose titrated amitriptyline as second-line treatment for adults with irritable bowel syndrome in primary care: the ATLANTIS RCT

Health Technology Assessment
Background Irritable bowel syndrome, characterised by abdominal pain and a change in stool form or frequency, is most often managed in primary care. When first-line therapies are ineffective, National Institute for Health and Care Excellence guidelines ...
Alexandra Wright-Hughes, Alexander C Ford, Sarah L Alderson, Pei Loo Ow, Matthew J Ridd, Robbie Foy, Felicity L Bishop, Matthew Chaddock, Heather Cook, Deborah Cooper, Catherine Fernandez, Elspeth A Guthrie, Suzanne Hartley, Amy Herbert, Daniel Howdon, Delia P Muir, Sonia Newman, Christopher A Taylor, Emma J Teasdale, Ruth Thornton, Hazel A Everitt, Amanda J Farrin   +21 more
doaj   +1 more source

The Ghent Psychotherapy Study (GPS) on the differential efficacy of supportive-expressive and cognitive behavioral interventions in dependent and self-critical depressive patients : study protocol for a randomized controlled trial [PDF]

, 2017
Background: Major depressive disorder is a leading cause of disease burden worldwide, indicating the importance of effective therapies. Outcome studies have shown overall efficacy of different types of psychotherapy across groups, yet large variability ...
Baeken, Chris, Bockting, Claudi, De Geest, Rosa, De Smet, Melissa, Desmet, Mattias, Hennissen, Vicky, Hermans, Goedele, Inslegers, Ruth, Loeys, Tom, Meganck, Reitske, Norman, Ufuoma Angelica, Truijens, Femke, Van Nieuwenhove, Kimberly, Vanheule, Stijn   +13 more
core   +3 more sources

The Global Airways in Practice: Long‐term Effects of Mepolizumab With or Without FESS on Type 2 Inflammation in Patients With CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease often associated with asthma. The global airway hypothesis suggests bidirectional inflammatory interactions between upper and lower airways. Mepolizumab, an anti–IL‐5 therapy, treats conditions systemically, while functional endoscopic sinus surgery ...
Jens Tidemandsen, Vibeke Backer, Anne Sophie Homøe, Thomas H. L. Jensen, Kasper Aanæs, Howraman Meteran, Morten Hostrup, Lukas Moesgaard, Christiane Haase, Peter G. Gibson   +9 more
wiley   +1 more source