Results 91 to 100 of about 3,544 (200)
Turkiye Klinikleri Journal of Medical Sciences, 2012 Objective: Organic phosphates (OP) bind covalently to acetylcholinesterase (AChE) and acetylcholine (Ach) accumulates in the synaptic cleft. Administering oximes before aging process causes breakage of the covalent bond between OP-AChE, and allows reactivation of AChE. Pralidoxime (PAM) is the most commonly used oxime.
Kozaci, Nalan +3 more
openaire +1 more source
Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication [PDF]
, 2014 Paraoxon (POX) is an active metabolite of organophosphate (OP) pesticide parathion that has been weaponized and used against civilian populations. Exposure to POX produces high mortality.
Blair, Robert E. +4 more
core +2 more sources
CHRISMED Journal of Health and Research, 2015 Organophosphorus (OP) compounds have been widely used as pesticide in India. Because of wide use and easy availability, it is the most common poisoning. OP compound poisoning can lead to cardiac complications.
Manoj Lakhotia +4 more
doaj +1 more source
Aerospace medicine and biology: A continuing bibliography with indexes (supplement 361) [PDF]
This bibliography lists 141 reports, articles and other documents introduced into the NASA Scientific and Technical Information System during Mar. 1992.
core +1 more source
Acta Medica, 1998 1. The therapeutic efficacy of various oximes (pralidoxime, obidoxime, methoxime, HI-6, HLö-7, BI-6) against supralethal nerve agent poisoning (soman, sarin, cyclosin) in mice was tested. 2. New oxime BI-6, synthesized in our laboratory, is significantly
Jiří Kassa
doaj +1 more source
Intensive care management of organophosphate insecticide poisoning [PDF]
, 2001 INTRODUCTION: Organophosphate (OP) insecticides inhibit both cholinesterase and pseudo-cholinesterase activities. The inhibition of acetylcholinesterase causes accumulation of acetylcholine at synapses, and overstimulation of neurotransmission occurs as ...
Güven, Muhammed, Sungur, Murat
core +2 more sources
Synthesis of o-aryloxime [PDF]
, 2012 An efficient CuI catalyst for the O-arylation of Benzaldoxime with aryl iodide has been developed.Here Benzaldooxime serves as an efficient for C-O cross-coupling thereby allowing for the preparation of O-aryloxime from simple aryl halide.This is a ...
Nayak, Manaswini, Pattnayak, Sagarika
core
Cholinergic Crisis after Rodenticide Poisoning
Western Journal of Emergency Medicine, 2010 Rodenticides have historically been common agents in attempted suicides. As most rodenticides in the United States (U.S.) are superwarfarins, these ingestions are generally managed conservatively with close monitoring for coagulopathy, and if necessary ...
Waseem, Muhammad +4 more
doaj
Renal Tubular Secretion of Pralidoxime in Man
Experimental Biology and Medicine, 1974 Abstract : Pralidoxime chloride is a quaternary ammonium compound used to reactivate organophosphate-inhibited cholinesterase. The drug is rapidly cleared from the plasma by renal tubular secretion, though the mechanism has not been specifically identified.
R D, Swartz, F R, Sidell
openaire +2 more sources
Accidental phosphine gas poisoning with fatal myocardial dysfunction in two families [PDF]
, 2015 Aluminum phosphide is commonly used as a rodenticide and insecticide and is one of the most fatal poisons. The active ingredient is Phosphine gas which inhibits cytochrome oxidase and cellular oxygen utilization.
Akhtar, Saleem +3 more
core +1 more source