Results 71 to 80 of about 2,059 (195)

Pharmacokinetic Studies on Oximes in Organophosphate Poisoning: A Mini Review [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2014
Organophosphate (OP) poisoning is one of the most common causes of poisoning in developing countries especially in Southeastern Asia. Poisoning with phosphorus-containing organic chemicals or OP compounds can be managed with antidotes like oximes which ...
Girish Thunga   +6 more
doaj  

Clinical study of continuous micropump infusion of atropine and pralidoxime chloride for treatment of severe acute organophosphorus insecticide poisoning [PDF]

open access: yes, 2015
BackgroundOur study sought to assess the effectiveness of a constant micropump infusion of atropine and pralidoxime chloride compared with repeated-bolus doses in patients with severe acute organophosphorus insecticide poisoning (AOPP).MethodsA total of ...
Liu, Chang-Fang   +2 more
core   +1 more source

Cardiogenic shock with 1° heart block after organophosphorus poisoning: A case report and review of cardiac complication in organophosphorus poisoning

open access: yesCHRISMED Journal of Health and Research, 2015
Organophosphorus (OP) compounds have been widely used as pesticide in India. Because of wide use and easy availability, it is the most common poisoning. OP compound poisoning can lead to cardiac complications.
Manoj Lakhotia   +4 more
doaj   +1 more source

Renal Tubular Secretion of Pralidoxime in Man

open access: yesExperimental Biology and Medicine, 1974
Abstract : Pralidoxime chloride is a quaternary ammonium compound used to reactivate organophosphate-inhibited cholinesterase. The drug is rapidly cleared from the plasma by renal tubular secretion, though the mechanism has not been specifically identified.
R D, Swartz, F R, Sidell
openaire   +2 more sources

Photoinduced electron transfer between quantum dots and pralidoxime: an efficient sensing strategy

open access: yes, 2017
Photoinduced electron transfer (PET)-mediated fluorescence quenching of CdTe/CdS quantum dots by pralidoxime (PAM).
K. Girish Kumar   +2 more
core   +1 more source

Bioavailability of diazepam after intramuscular injection of its water-soluble prodrug alone or with atropine–pralidoxime in healthy volunteers [PDF]

open access: yes, 2009
Background and purpose:  The aim of this study was to assess the relative bioavailability of diazepam after administration of diazepam itself or as a water-soluble prodrug, avizafone, in humans. Experimental approach:  The study was conducted in an open,
C. Abbara   +15 more
core   +1 more source

A Comparison of the Therapeutic Efficacy of Conventional and Modern Oximes Against Supralethal Doses of Highly Toxic Organophosphates in Mice

open access: yesActa Medica, 1998
1. The therapeutic efficacy of various oximes (pralidoxime, obidoxime, methoxime, HI-6, HLö-7, BI-6) against supralethal nerve agent poisoning (soman, sarin, cyclosin) in mice was tested. 2. New oxime BI-6, synthesized in our laboratory, is significantly
Jiří Kassa
doaj   +1 more source

Cholinergic Crisis after Rodenticide Poisoning

open access: yesWestern Journal of Emergency Medicine, 2010
Rodenticides have historically been common agents in attempted suicides. As most rodenticides in the United States (U.S.) are superwarfarins, these ingestions are generally managed conservatively with close monitoring for coagulopathy, and if necessary ...
Waseem, Muhammad   +4 more
doaj  

The Efficacy of Pralidoxime in the Treatment of Organophosphate Poisoning in Humans: A Systematic Review and Meta-analysis of Randomized Trials

open access: yes, 2020
Introduction The benefits of atropine in the treatment of acute organophosphate (OP) poisoning has been well established, while that of oximes is still uncertain. Pralidoxime is the most often used oxime worldwide.
Kharel, Himal   +3 more
core   +1 more source

Use of pralidoxime-Pd(II) complex for the spectrophotometric determination of the cholinesterase reactivator (PAM-2Cl) in the urine

open access: yes, 1990
A simple and rapid method for the spectrophotometric determination of pralidoxime chloride in urine, based on complex formation with palladium(II) without preliminary mineralization of the sample, is described.
Karljiković-Rajić, Katarina   +1 more
core   +1 more source

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