Results 91 to 100 of about 2,868 (201)

A Comparison of the Therapeutic Efficacy of Conventional and Modern Oximes Against Supralethal Doses of Highly Toxic Organophosphates in Mice

open access: yesActa Medica, 1998
1. The therapeutic efficacy of various oximes (pralidoxime, obidoxime, methoxime, HI-6, HLö-7, BI-6) against supralethal nerve agent poisoning (soman, sarin, cyclosin) in mice was tested. 2. New oxime BI-6, synthesized in our laboratory, is significantly
Jiří Kassa
doaj   +1 more source

Colorimetric Detection of Warfare Gases by Polydiacetylenes Toward Equipment‐Free Detection [PDF]

open access: yes, 2012
Rationally designed polydiacetylene (PDA) molecules have been developed for rapid, selective, sensitive, and convenient colorimetric detection of organophosphate (OP) nerve agents, a mass destruction weapon. Oxime (OX) functionality was incorporated into
Ahn   +33 more
core   +1 more source

Synthesis of o-aryloxime [PDF]

open access: yes, 2012
An efficient CuI catalyst for the O-arylation of Benzaldoxime with aryl iodide has been developed.Here Benzaldooxime serves as an efficient for C-O cross-coupling thereby allowing for the preparation of O-aryloxime from simple aryl halide.This is a ...
Nayak, Manaswini, Pattnayak, Sagarika
core  

Cholinergic Crisis after Rodenticide Poisoning

open access: yesWestern Journal of Emergency Medicine, 2010
Rodenticides have historically been common agents in attempted suicides. As most rodenticides in the United States (U.S.) are superwarfarins, these ingestions are generally managed conservatively with close monitoring for coagulopathy, and if necessary ...
Waseem, Muhammad   +4 more
doaj  

Accidental phosphine gas poisoning with fatal myocardial dysfunction in two families [PDF]

open access: yes, 2015
Aluminum phosphide is commonly used as a rodenticide and insecticide and is one of the most fatal poisons. The active ingredient is Phosphine gas which inhibits cytochrome oxidase and cellular oxygen utilization.
Akhtar, Saleem   +3 more
core   +1 more source

Renal Tubular Secretion of Pralidoxime in Man

open access: yesExperimental Biology and Medicine, 1974
Abstract : Pralidoxime chloride is a quaternary ammonium compound used to reactivate organophosphate-inhibited cholinesterase. The drug is rapidly cleared from the plasma by renal tubular secretion, though the mechanism has not been specifically identified.
R D, Swartz, F R, Sidell
openaire   +2 more sources

Novel Bisquaternary Oximes—Reactivation of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon

open access: yesMolecules, 2009
Four novel bisquaternary aldoxime cholinesterase reactivators differing in their chemical structure were prepared. Afterwards, their biological activity was evaluated for their ability to reactivate acetylcholinesterase (AChE; EC 3.1.1.7) and ...
Daniel Jun   +9 more
doaj   +1 more source

Effectiveness of High Dose Pralidoxime for Treatment of Organophosphate Poisoning [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2014
Background: For effective treatment of organophosphate (OP) poisoning, development of a standardized protocol with flexible dose regimen for atropine and pralidoxime is an essential step.
Pham Due
doaj  

Aerospace Medicine and Biology: A continuing bibliography with indexes (supplement 291) [PDF]

open access: yes
This bibliography lists 131 reports, articles and other documents introduced into the NASA scientific and technical information system in November ...

core   +1 more source

Organophosphorous neurotoxic antidotes : Pharmacokinetic analysis of avizafone hydrolysis and pralidoxime [PDF]

open access: yes, 2008
Date du colloque : 04 ...
A. Cailleux   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy