Results 151 to 160 of about 2,059 (195)
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Effect of intravenous thiamine on pralidoxime kinetics

Clinical Pharmacology & Therapeutics, 1978
Subjects were given pralidoxime chloride (5 mg/kg, intravenously) alone and again while they were receiving an infusion of thiamine hydrochloride. After the addition of thiamine: (1) overall, the urinary excretion of oxime was the same but the amount excreted in the first three hours was smaller; (2) the plasma half‐life of oxime lengthened; (3) the ...
J, Josselson, F R, Sidell
openaire   +2 more sources

Pralidoxime Chloride With Atropine in Dimpylate Poisoning

JAMA: The Journal of the American Medical Association, 1969
To the Editor:— Pralidoxime (Protopam) chloride is a cholinesterase reactivator that has been recommended in the treatment of organic phosphate intoxications. Pralidoxime (2 PAM), however, is contraindicated in carbamate poisoning. It appears to be most effective when used in conjunction with atropine therapy.
openaire   +2 more sources

Pralidoxime and oximes

2022
Alexander F. Barbuto, Michele M. Burns
openaire   +1 more source

pralidoxime

2009
Guillaume Chevrel, Virginie Dessus
openaire   +1 more source

Pralidoxime hydrolysis of thiocholine esters.

Veterinary and human toxicology, 2003
Pralidoxime (2-PAM) hydrolyzes both acetylthiocholine and butytylthiocholine in an apparent first-order manner, with higher rates observed at pH 8.0 compared to those at pH 7.4. When the reaction is followed by the decrease in pH due to hydrolysis, pralidoxime hydrolyzes acetylthiocholine but not acetylcholine or succinylcholine.
Richard G, Pannbacker   +1 more
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Pralidoxime Chloride

1988
Umesh V. Bariakar, Urvashi N. Patel
openaire   +1 more source

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