Results 161 to 170 of about 12,380 (194)

On the Metabolism of Prasugrel

Revista Española de Cardiología (English Edition), 2011
Hemos leido con interes el editorial de los Dres. Freedman e Iafrati recientemente publicado en REVISTA ESPANOLA DE CARDIOLOGIA. En dicho editorial, se menciona que el prasugrel es un inhibidor del receptor P2Y12 que no se metaboliza en el higado y no parece verse afectado por la variabilidad de la isoenzima P450.
Carlos Felipe, Barrera-Ramírez, Luis Ramón, Pineda-Pompa, Carlos E, Guzmán-Rodríguez   +2 more
openaire   +2 more sources

Adjusted indirect comparison meta-analysis of prasugrel versus ticagrelor for patients with acute coronary syndromes

International Journal of Cardiology, 2011
Background: Clopidogrel is beneficial after ACS. Recent data suggest the superiority of prasugrel or ticagrelor compared with clopidogrel. However, there is no comparison of prasugrel vs. ticagrelor.
Giuseppe Biondi-Zoccai, Marzia Lotrionte, Pierfrancesco Agostoni   +2 more
exaly   +2 more sources

Prasugrel Hydrochloride

2015
A comprehensive profile of prasugrel HCl is reported herein with 158 references. A full description including nomenclature, formulae, elemental analysis, and appearance is included. Methods of preparation for prasugrel HCl, its intermediates, and derivatives are fully discussed.
Mahmoud M H, Al Omari, Nidal A, Qinna, Iyad S, Rashid, Khaldoun A, Al-Sou'od, Adnan A, Badwan   +4 more
openaire   +2 more sources

Prasugrel and ticagrelor

Journal of Cardiovascular Medicine, 2014
Clopidogrel is a prodrug that undergoes extensive enteric clearance and requires two-stage hepatic activation by cytochrome P450 (CYP) enzymes. This metabolic pathway is susceptible to genetic polymorphisms, resulting in a variable platelet inhibitory effect.
Nuccia, Morici, Paola, Colombo, Antonio, Mafrici, Jacopo A, Oreglia, Silvio, Klugmann, Stefano, Savonitto   +5 more
openaire   +2 more sources

Prasugrel

Nature Reviews Drug Discovery, 2009
Kurt Huber, Uma Yasothan, Bashar Hamad, Peter Kirkpatrick   +3 more
  +4 more sources

Prasugrel

Reactions Weekly, 2023
  +4 more sources

Prasugrel

Reactions Weekly, 2022
openaire   +2 more sources

Prasugrel ☆

Reactions Weekly, 2017
  +6 more sources

Effect of the Novel Thienopyridine Prasugrel Compared With Clopidogrel on Spontaneous and Procedural Myocardial Infarction in the Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel–Thrombolysis in Myocardial Infarction 38

Circulation, 2009
David A Morrow, Harvey D White, JOSÉ C Nicolau   +2 more
exaly  

Prasugrel

Practical Diabetes International, 2011
N Sidik, G McKay, M Fisher
openaire   +1 more source