Results 41 to 50 of about 9,741 (153)

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 928-941, April 2026.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park, Jae‐Hwan Lee, Jin‐Ok Jeong, Diana A. Gorog, Udaya S. Tantry, Byeong‐Keuk Kim, Hyung Joon Joo, Kiyuk Chang, Jin‐Yong Hwang, Young Bin Song, Sung Gyun Ahn, Jung‐Won Suh, Woong Gil Choi, Jung Rae Cho, Jeehoon Kang, Sang Yeub Lee, Hyo‐Soo Kim, Moo Hyun Kim, Do‐Sun Lim, Eun‐Seok Shin, Paul A. Gurbel, Young‐Hoon Jeong, on behalf of the PTRG‐DES Consortium Investigators   +22 more
wiley   +1 more source

P2Y₁₂ Receptor Inhibitors in the Treatment of Patients with Acute Coronary Syndrome and Percutaneous Coronary Intervention: Possibilities of Prasugrel

Рациональная фармакотерапия в кардиологии, 2019
The possibilities of P2Y12 receptor inhibitors application in the treatment of patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) are discussed in the article.
N. M. Vorobyeva
doaj   +1 more source

Elevated triglyceride‐glucose index is associated with increased risk of chronic kidney disease and end‐stage renal disease in type 1 diabetes: Nationwide cohort study

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2784-2794, April 2026.
Abstract Aims Prognostic markers for microvascular complications in type 1 diabetes are needed because factors beyond hyperglycaemia contribute to this risk. The triglyceride‐glucose (TyG) index is an established marker of vascular complications in type 2 diabetes; however, its clinical significance in type 1 diabetes remains unknown.
Rosa Oh, Seohyun Kim, So Hyun Cho, Ji Yoon Kim, Myunghwa Jang, Sang Ho Park, You‐Bin Lee, Sang‐Man Jin, Kyu Yeon Hur, Gyuri Kim, Jae Hyeon Kim   +10 more
wiley   +1 more source

Impact of Proton Pump Inhibitor Use on the Comparative Effectiveness and Safety of Prasugrel Versus Clopidogrel: Insights From the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE‐ACS) Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundProton pump inhibitors (PPIs) reduce gastrointestinal bleeding events but may alter clopidogrel metabolism. We sought to understand the comparative effectiveness and safety of prasugrel versus clopidogrel in the context of proton pump inhibitor
Larry R. Jackson, Eric D. Peterson, Lisa A. McCoy, Christine Ju, Marjorie Zettler, Brian A. Baker, John C. Messenger, Douglas E. Faries, Mark B. Effron, David J. Cohen, Tracy Y. Wang   +10 more
doaj   +1 more source

Prior Myocardial Infarction and Treatment Effect of Ticagrelor Versus Prasugrel in Patients With Acute Coronary Syndromes ‐ A Post‐hoc Analysis of the ISAR‐REACT 5 Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background The efficacy and safety of ticagrelor versus prasugrel in patients with acute coronary syndrome and prior myocardial infarction (MI) remain unstudied. We aimed to assess the treatment effect of ticagrelor versus prasugrel according to prior MI
Shqipdona Lahu, Maria Scalamogna, Gjin Ndrepepa, Maurizio Menichelli, Christian Valina, Rayyan Hemetsberger, Bernhard Witzenbichler, Isabell Bernlochner, Michael Joner, Erion Xhepa, Alexander Hapfelmeier, Sebastian Kufner, Hendrik B. Sager, Katharina Mayer, Thorsten Kessler, Karl‐Ludwig Laugwitz, Gert Richardt, Heribert Schunkert, Franz‐Josef Neumann, Adnan Kastrati, Salvatore Cassese   +20 more
doaj   +1 more source

Assessment of Quality of Care Provided for Patients Receiving Post‐Myocardial Infarction Care at Selected Cardiac Clinics in Sulaymaniyah: Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background According to global projections, by the year 2050, ischemic heart disease will remain the leading cause of cardiovascular deaths with hypertension as a leading modifiable risk factor for mortality. Improving quality care for patients with acute myocardial infarction (MI) is associated with improved outcomes. Aims There is inadequate
Banaz Sadiq Elias, Yara Sarwar Hamid, Mende Mensa Sorato   +2 more
wiley   +1 more source

Outcomes of Aquablation in BPH with bladder stones: Analysis of the ICARUS database

BJUI Compass, Volume 7, Issue 2, February 2026.
Abstract Objective The purpose of this study is investigate the clinical outcomes of men with benign prostatic hyperplasia (BPH) and bladder stones treated concomitantly with Aquablation and bladder stone removal in an international, multi‐institutional cohort.
Joshua D. Cabral, Margaret Gannon, Gregory Raster, David J. Nusbaum, David Bouhadana, Adel Arezki, Aalya Hamouda, Anouk Leathead, Ilan Ohana, Rosie Foucault, Iman Sadri, Jeffrey A. Sioufi, Nick Lee, Tarek Benzouak, Liam Murad, Nicholas J. Corsi, John Klein, Inderjit Singh, James Kearns, Cecilia Chang, Juan Justo Quintas, Kevin C. Zorn, Tiago Rodrigues, Shawn H. Marhamati, Brian T. Helfand, Alexander P. Glaser   +25 more
wiley   +1 more source

A study on the impact of CYP2C19 genotype and platelet reactivity assay on patients undergoing PCI

Indian Heart Journal, 2015
Background: A thorough understanding of the patient's genotype and their functional response to a medication is necessary for improving event free survival.
P.C. Rath, Sundar Chidambaram, Pallavi Rath, Byomakesh Dikshit, Sudhir Naik, Prashant K. Sahoo, Brajraj Das, Mohanshankar Mahalingam, Lakshmipathi Khandrika, Jugnu Jain   +9 more
doaj   +1 more source

Safety and efficacy of Rezūm water vapour energy therapy in BPH patients receiving antithrombotic therapy: A Japanese single‐centre experience

BJUI Compass, Volume 7, Issue 2, February 2026.
Abstract Objectives The objective of this study is to evaluate the safety and efficacy of Rezūm water vapour energy therapy (WAVE) in Japanese patients with benign prostatic hyperplasia (BPH) continuing antithrombotic therapy and to validate the Okayama University Modified Clavien‐Dindo classification (OU‐mCD) for perioperative hematuria.
Takatoshi Moriwake, Yusuke Tominaga, Satoshi Katayama, Haruki Kaku, Ichiro Tsuboi, Kasumi Yoshinaga, Tomoaki Yamanoi, Tatsushi Kawada, Takuya Sadahira, Takehiro Iwata, Shingo Nishimura, Kensuke Bekku, Yasuhiro Katayama, Motoo Araki   +13 more
wiley   +1 more source

Extended Dual Versus Single Anti‐Platelet Therapy Following Percutaneous Coronary Intervention: A Bayesian Meta‐Analysis and Regression on All‐Cause Mortality

Catheterization and Cardiovascular Interventions, Volume 107, Issue 2, Page 510-519, February 1, 2026.
ABSTRACT Introduction Current ESC/EACTS guidelines recommend standard‐duration dual antiplatelet therapy (DAPT) following percutaneous coronary intervention (PCI). However, the subsequent transition to either extended DAPT or single antiplatelet therapy (SAPT) remains debated due to limited comparative outcome data. This Bayesian meta‐analysis and meta‐
Faizan Ahmed, Faseeh Haider, Ramsha Ali, Muhammad Arham, Najam Gohar, Ayesha Batool, Sara Sharif, Muhammad Huzaifa Ahmed Khan, Zuha Tariq, Syeda Simrah Shah, Aman Ullah, Ahsan Alam, Syed Shah Qasim Hamdani, Muhammad Usman, Tehmasp Rehman Mirza, Yasar Sattar, Swapnil Patel, Jesus Almendral, Ameer Haider Cheema, Fawaz Alenezi   +19 more
wiley   +1 more source