Results 21 to 30 of about 29,845 (261)

Sigmoid Schistosomiasis Granuloma Manifested as a Large Painless Supra-Pubic Mass: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Schistosomiasis remains a prevalent parasitic disease in tropical and subtropical regions, ranking second to malaria in terms of parasitic burden. The disease manifests in two primary forms: urinary schistosomiasis, caused by Schistosoma haematobium, and intestinal schistosomiasis, associated with S. mansoni and S. japonicum.
Badri R, Abdalrhim S, Hamid A, Salah Aldeen A, Tahir A, Ahmad MO.   +5 more
europepmc   +2 more sources

Potential cost-effectiveness of schistosomiasis treatment for reducing HIV transmission in Africa--the case of Zimbabwean women. [PDF]

PLoS Neglected Tropical Diseases, 2013
Epidemiological data from Zimbabwe suggests that genital infection with Schistosoma haematobium may increase the risk of HIV infection in young women. Therefore, the treatment of Schistosoma haematobium with praziquantel could be a potential strategy for
Martial L Ndeffo Mbah, Eric M Poolman, Katherine E Atkins, Evan W Orenstein, Lauren Ancel Meyers, Jeffrey P Townsend, Alison P Galvani   +6 more
doaj   +1 more source

Uptake of preventive treatment for intestinal schistosomiasis among school children in Jinja district, Uganda: a cross sectional study. [PDF]

PLoS ONE, 2013
BACKGROUND: In Uganda, the current national health sector strategic and investment plan underscores schistosomiasis as one of the diseases targeted for elimination by the year 2015.
Simon Muhumuza, Annette Olsen, Anne Katahoire, Fred Nuwaha   +3 more
doaj   +1 more source

Preformulation and Long-Term Stability Studies of an Optimized Palatable Praziquantel Ethanol-Free Solution for Pediatric Delivery

Pharmaceutics, 2023
To date, the treatment for cysticercosis and neurocysticercosis consists of a single oral intake of praziquantel (5–10 mg/kg), which since it is only available as tablets, hinders its administration to pediatric patients.
Giselle Bedogni, Paula Garcia, Katia Seremeta, Nora Okulik, Claudio Salomon   +4 more
doaj   +1 more source

Solid dispersions with hydrogenated castor oil increase solubility, dissolution rate and intestinal absorption of praziquantel

Brazilian Journal of Pharmaceutical Sciences, 2010
The solubility behavior of drugs remains one of the most challenging aspects in formulation development. Solid Dispersion (SD) has tremendous potential for improving drug solubility.
Marco Vinicius Chaud, Pollyanna Tamascia, Andréa Cristina de Lima, Maria Ondina Paganelli, Maria Palmira Daflon Gremião, Osvaldo de Freitas   +5 more
doaj   +1 more source

New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to treatment with praziquantel [PDF]

, 2015
By 2020, the global health community aims to control and eliminate human helminthiases, including schistosomiasis in selected African countries, principally by preventive chemotherapy (PCT) through mass drug administration (MDA) of anthelminthics ...
A Danso-Appiah, A Fenwick, A Montresor, A Vidyashankar, AC Gelman, AE Butterworth, AL Bustinduy, Alexandra U. Scherrer, AU Scherrer, B Levecke, BM Bolker, CH King, Charles H. King, CJL Murray, CL Black, D Alonso, D Bates, F Thiongo, G Raso, Giovanna Raso, GR Olds, IM Silva, J Cabaret, J Modha, J Smith, J Utzinger, J Utzinger, J Utzinger, J. Russell Stothard, JA Hanley, JC Sousa-Figueiredo, JD Hadfield, Jean T. Coulibaly, José Carlos Sousa-Figueiredo, JP Webster, JT Coulibaly, Jürg Utzinger, K Stete, Katarina Stete, M Albonico, M Booth, M Ismail, M Nielsen, M Reddy, M Walker, Maria-Gloria Basáñez, Martin Walker, ME Mejía, MEJ Woolhouse, MG Basáñez, MJ Bockarie, MJ Doenhoff, MJ Doenhoff, P Andrews, P Fallon, PH Lamberton, Piero L. Olliaro, PJ Brindley, PJ Diggle, PJ Hotez, PL Olliaro, PNM Mwinzi, R Core Team, S Anayi, SD Melman, SJ Vlas de, SN Lahiri, SV Subramanian, Tarub S. Mabud, TW Jia, U Halekoh, W Harnett, W Wang, World Health Organization, World Health Organization, World Health Organization   +75 more
core   +4 more sources

Praziquantel coverage in schools and communities targeted for the elimination of urogenital schistosomiasis in Zanzibar: a cross-sectional survey [PDF]

, 2015
© 2015 Knopp et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any ...
Ali, SM, Ame, SM, Blair, L, Fenwick, A, Juma, S, Khamis, IS, Knopp, S, Mohammed, KA, Muhsin, J, Person, B, Rabone, M, Rollinson, D   +11 more
core   +2 more sources

The study of base and surface-active substances influence on biopharmaceutical characteristics of suppository with praziquantel

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Acne dermatoses (rosacea, perioral dermatitis, seborrheic dermatitis etc.) are one of the most actual problems in dermatology. Praziquantel is an antiparasitic medication effective towards trematodes, cestodes.
D. M. Romanina, V. V. Gladishev, G. P. Lisyanska   +2 more
doaj   +1 more source

Resolution of Praziquantel

PLoS Neglected Tropical Diseases, 2011
Praziquantel remains the drug of choice for the worldwide treatment and control of schistosomiasis. The drug is synthesized and administered as a racemate. Use of the pure active enantiomer would be desirable since the inactive enantiomer is associated with side effects and is responsible for the extremely bitter taste of the pill.We have identified ...
Jesse M. de Gooijer, Michael Woelfle, Jean-Paul Seerden, Kees Pouwer, Matthew H. Todd, Piero Olliaro   +5 more
openaire   +5 more sources

Single oral fixed-dose praziquantel-miltefosine nanocombination for effective control of experimental schistosomiasis mansoni

Parasites & Vectors, 2020
Background The control of schistosomiasis has been centered to date on a single drug, praziquantel, with shortcomings including treatment failure, reinfection, and emergence of drug resistance. Drug repurposing, combination therapy or nanotechnology were
Maha M. Eissa, Mervat Z. El-Azzouni, Labiba K. El-Khordagui, Amany Abdel Bary, Riham M. El-Moslemany, Sara A. Abdel Salam   +5 more
doaj   +1 more source